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Lurasidonhydrochloride 367514-88-3 C28H36N4O2S
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Lurasidone hydrochloride Basic information |
Product Name: | Lurasidone hydrochloride |
Synonyms: | Lurasidonhydrochloride;Lurasidonhydrochlorid;(3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride;(1R,2S,3R,4S)-N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinylMethyl]-1-cyclohexylMethyl]-2,3-bicyclo[2.2.1]heptanedicarboxyiMide hydrochloride;Latuda, SM 13496;Lurasidone Hydrochlorid;(3aR,4S,7R,7aS)-2-[(1R,2R)-2-[4-(1,2-Benzisothiazol-3-yl)piperazin-1-ylMethyl]cyclohexylMethyl]hexahydro-1H-4,7-Methanoisoindole-1,3-dione hydrochloride;4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, hydrochloride (1:1), (3aR,4S,7R,7aS)- |
CAS: | 367514-88-3 |
MF: | C28H36N4O2S |
MW: | 492.684 |
EINECS: | 200-659-6 |
Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 367514-88-3.mol |
Lurasidone hydrochloride Chemical Properties |
Melting point | 198-205°C |
Fp | 9℃ |
storage temp. | Refrigerator |
InChIKey | PQXKDMSYBGKCJA-CVTJIBDQSA-N |
Safety Information |
Hazard Codes | F,T |
Risk Statements | 11-23/24/25-39/23/24/25 |
Safety Statements | 7-16-36/37-45 |
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
Lurasidone hydrochloride Usage And Synthesis |
Chemical Properties | Off-White Solid |
Uses | Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively |
Uses | An antipsychotic used for treatment of schizophrenia. |
Definition | ChEBI: A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia. |
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