Esculetin Basic information
Product Name: Esculetin
Synonyms: CICHORIGENIN;CICHERINGENIN;ESCULETOL;ESCULETIN;LABOTEST-BB LT00233229;AESCULETIN;AKOS 215-98;6,7-DIHYDROXY-CHROMEN-2-ONE
CAS: 305-01-1
MF: C9H6O4
MW: 178.14
EINECS: 206-161-5
Product Categories: Coumarins;Analytical Chemistry;Mass Spectrometry;Matrix Materials (MALDI-TOF-MS);chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Coumarin;Fluorescent
Mol File: 305-01-1.mol
Esculetin Structure
Esculetin Chemical Properties
Melting point 271-273 °C(lit.)
storage temp. 2-8°C
solubility Solubility Almost insoluble in boiling water, ether; soluble in hot ethanol, glacial acetic acid
form powder
pka 1.71(at 25℃)
color Light yellow
PH Range Weak blue uorescence (1.5) to strong blue uorescence (2.0)
Water Solubility slightly soluble
Merck 14,3697
BRN 152788
Major Application antiinflammatory, Herbicides, cosmetics, teeth whitening agent, antifungal, neurodegenerative andfungal, antibacterial, antiviral, treating drug-induced weight gain, neurodegenerative and blood coagulation disorders, cancer, amyloidosis, skin impairments and baldness
CAS DataBase Reference 305-01-1(CAS DataBase Reference)
NIST Chemistry Reference Coumarin, 6,7-dihydroxy-(305-01-1)
EPA Substance Registry System 2H-1-Benzopyran- 2-one, 6,7-dihydroxy-(305-01-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS GN6382500
HS Code 29322090
MSDS Information
Provider Language
6,7-Dihydroxycoumarin English
ACROS English
SigmaAldrich English
ALFA English
Esculetin Usage And Synthesis
Chemical Properties YELLOWISH CRYSTALLINE POWDER
Uses antifungal, hepatoprotective, IL-1 inhibitor
Definition ChEBI: A hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.
Uses In filters for absorption of ultraviolet light.
Esculetin Preparation Products And Raw materials
Preparation Products SCOPARONE
Raw materials 1,4-Benzoquinone