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Camostat mesilate 59721-29-8 C21H26N4O8S
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Camostat mesilate Basic information |
Product Name: | Camostat mesilate |
Synonyms: | 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-benzeneaceticaci2-(dimethylam;ino)-2-oxoethylester,monomethanesulfonate;n,n-dimethylcarbamoylmethyl4-(4-guanidinobenzoyloxy)phenylacetatemethanesul;p-(p-guanidinobenzoyloxy)phenylaceticacid,n,n-dimethylcarbamoylmethyleste;CAMOSTAT MESILATE;CAMOSTAT MESYLATE;Camostatemesylate;2-(Dimethylamino)-2-oxoethyl 4-(4-guanidinobenzoyloxy)phenylacetate methanesulphonate |
CAS: | 59721-29-8 |
MF: | C21H26N4O8S |
MW: | 494.52 |
EINECS: | |
Product Categories: | All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate |
Mol File: | 59721-29-8.mol |
|
Camostat mesilate Chemical Properties |
Melting point | 150-1550C |
RTECS | CY1571620 |
storage temp. | Desiccate at RT |
solubility | H2O: ≥24mg/mL |
color | white to tan |
Water Solubility | Soluble in water (100 mM), DMSO (100 mM), and ethanol (<1 mg/ml). |
Merck | 14,1728 |
CAS DataBase Reference | 59721-29-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,N |
Risk Statements | 36/37/38-50 |
Safety Statements | 26-61 |
RIDADR | UN 3077 9 / PGIII |
HazardClass | 9 |
Camostat mesilate Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Uses | Orally active, non-peptide proteolitic enzyme inhibitor with anti-trypsin and anti-plasmin activities, related structurally to gabexate. Protease inhibitor |
Biological Activity | Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration. |
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