Candesartan Basic information
Product Name: Candesartan
Synonyms: 2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylic acid;2-ETHOXY-1-[[2'-(1H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL]METHYL]-1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID;CANDESARTAN;CV-11974;CILEXITIL;Candesartan[CandesartanCilexetilIntermediates];Candesartan ( For Candesartan Cilexetil );2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid, CV-11974
CAS: 139481-59-7
MF: C24H20N6O3
MW: 440.45
EINECS:
Product Categories: Active Pharmaceutical Ingredients;Candesartan Cilexetil;API intermediates;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Candesartan Cilexatil;Aromatics;Heterocycles;Pharmaceutical raw material;Isotope
Mol File: 139481-59-7.mol
Candesartan Structure
Candesartan Chemical Properties
Melting point 183-185°C
RTECS DD6671000
storage temp. -20°C Freezer
Water Solubility Soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).
CAS DataBase Reference 139481-59-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-60-36/37-9
HS Code 29419000
Hazardous Substances Data 139481-59-7(Hazardous Substances Data)
MSDS Information
Provider Language
2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-benzoimidazole-4-carboxylic acid English
Candesartan Usage And Synthesis
Chemical Properties Crystalline Solid
Uses An angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive
Uses antihypertensive, angiotensin II inhibitor
Definition ChEBI: A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin eceptor antagonist used for the treatment of hypertension.
Candesartan Preparation Products And Raw materials
Raw materials Thionyl chloride-->Potassium carbonate-->Trifluoroacetic acid-->tert-Butanol-->Sodium azide-->Benzyl bromide-->Mineral oil-->3-Nitrophthalic acid