3690-10-6 ZEBULARINE 98%
CAS No.3690-10-6
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ZEBULARINE Basic information |
Product Name: | ZEBULARINE |
Synonyms: | 1-(β-d-ribofuranosyl)-1,2-dihydropyrimidin-2-one;pyrimidin-2-one beta-ribofuranoside;1--D-Ribofuranosyl-2(1H)-pyrimidinone;4-Deoxyuridine;NSC 309132;Pyrimidin-2-one -D-Ribofuranoside;1-(β-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one, 2-Pyrimidone-1-β-D-riboside;2(1H)-PyriMidinone, 1-b-D-ribofuranosyl- |
CAS: | 3690-10-6 |
MF: | C9H12N2O5 |
MW: | 228.203 |
EINECS: | 2017-001-1 |
Product Categories: | Carbohydrates & Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 3690-10-6.mol |
|
ZEBULARINE Chemical Properties |
Melting point | 160-162 C |
storage temp. | 2-8°C |
solubility | DMSO: 16 mg/mL, soluble |
form | solid |
Safety Information |
WGK Germany | 3 |
RTECS | UW7539720 |
ZEBULARINE Usage And Synthesis |
Chemical Properties | White Solid |
Uses | It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent |
Biological Activity | Orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC 50 = 120 μ M) and re-activates silenced genes in T24 bladder carcinoma cells. Also inhibits cytidine deaminase (K i ~ 2 μ M). |
ZEBULARINE Preparation Products And Raw materials |
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