NewblueCHEM--118288...

NewblueCHEM--118288-08-7---Lafutidine

NewblueCHEM--118288-08-7---Lafutidine

Min.Order / FOB Price:Get Latest Price

1 Metric Ton

FOB Price: USD 500.0000

  • Min.Order :1 Metric Ton
  • Purity: 99%
  • Payment Terms : L/C,T/T

Keywords

TIANFUCHEM--118288-08-7---Lafutidine TIANFUCHEM--118288-08-7---Lafutidine TIANFUCHEM--118288-08-7---Lafutidine

Quick Details

  • Appearance:white powder
  • Application:Pharmaceutical intermediates
  • PackAge:bag
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:Room temperature
  • Transportation:by sea

Superiority:

 
Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
 
 
 
1.Noble Metal Catalysts (Pt.Pd...)
 
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
 
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
 
4.Customs Synthesis
 
 
 
Our advantage:
 
 
 
1. Higest quality and good package
 
2.Fast delivery
 
3.Better payment term
 
4.Fast response to customer  within 6 hours
 
5.Good business credit in Europe ,US ,Japan ,Korea
 
 
 
Anyway ,if you need any chemicals from China ,Henan Newblue can help you

Details:

 
  Product Name:LafutidineSynonyms:n-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide;LAFUTIDINE;(+-)-2-(furfurylsulfinyl)-n-(4-(4-(piperidinomethyl)-2-pyridyl)oxy-(z)-2-but;(z)-inyl)oxy)-2-butenyl);acetamide,2-((2-furanylmethyl)sulfinyl)-n-(4-((4-(1-piperidinylmethyl)-2-pyrid;enyl)acetamide;frg-8813;LAFUTIDINE(SUBJECTTOPATENTFREE)CAS:118288-08-7MF:C22H29N3O4SMW:431.55EINECS:Product Categories:Active Pharmaceutical Ingredients;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Other APIsMol File:118288-08-7.mol
Lafutidine Chemical Properties
Melting point 92.7-94.9°CAS DataBase Reference118288-08-7(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
MSDS Information
Lafutidine Usage And Synthesis
DescriptionLafutidine is a second generation of H2-receptor antagonist. H2-receptor antagonist can strongly inhibit gastric acid secretion compared with conventional drugs such as antacids. Unlike conventional H2-receptor antagonist, lafutidine inhibits gastric acid secretion during daytime as well as nighttime in clinical studies in humans. Lafutidine also has gastroprotective activity independent of its acid antisecretory efficacy, preventing noxious agent-induced gastric mucosal injury and accelerating the repair process following gastric mucosal damage. It also protects experimentally induced reflux esophagitis, indomethacin-induced intestinal, and dextran sulfate sodium-induced colonic inflammation.
Lafutidine is used for gastric and duodenal ulcers. It is also confirmed that lafutidine can be used as an empiric treatment and superior efficacy for primary care practice patients with dyspepsia.References[1] Tomohiko Shimatani, Masaki Inoue, Tomoko Kuroiwa, Jing Xu, Masuo Nakamura, Susumu Tazuma, Kazuro Ikawa, Norifumi Morikawa (2006) Lafutidine, a Newly Developed Antiulcer Drug, Elevates Postprandial Intragastric pH and Increases Plasma Calcitonin Gene-Related Peptide and Somatostatin Concentrations in Humans: Comparisons with Famotidine, Digestive Diseases and Sciences, 51, 114-120
[2] Bhupesh Dewan, Nisha Philipose (2011) Lafutidine 10 mg versus Rabeprazole 20 mg in the Treatment of Patients with Heartburn-Dominant Uninvestigated Dyspepsia: A Randomized, Multicentric Trial, Gastroenterology Research and Practice, 2011, Article ID 640685
[3] # generation histamine H2-receptor antagonist. AntiulcerativeUsesLafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion

 

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