TIANFUCHEM--123040-16-4--Azasetron hydrochloride

 Product Name:Azasetron hydrochlorideSynonyms:N-(1-Azabicyclo[2.2.2]octane-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide·hydrochloride;6-chloro-3-keto-4-methyl-N-quinuclidin-3-yl-1,4-benzoxazine-8-carboxamide hydrochloride;N-{1-azabicyclo[2.2.2]octan-3-yl}-6-chloro-4-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxaMide;Azastron hydrochloride injection;N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxaMide hydrochloride (1:1);N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, hydrochloride (1:1);N-1-AZABICYCLO[2.2.2]-OCT-3-YL-6-CHLORO-3,4-DIHYDRO-4-METHYL-3-OXO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE, HYDROCHLORIDE;N-(1-AZABICYCLO[2.2.2]OCT-3-YL)-6-CHLORO-4-METHYL-3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE HCLCAS:123040-16-4MF:C17H21Cl2N3O3MW:386.27EINECS:Product Categories:anti-emetic;Serotonin receptorMol File:123040-16-4.mol
Azasetron hydrochloride Chemical Properties
Melting point 281° (dec); mp 305° (dec) (Kawakita)storage temp. Desiccate at -20°CCAS DataBase Reference123040-16-4(CAS DataBase Reference)
Safety Information
MSDS Information
Azasetron hydrochloride Usage And Synthesis
Chemical PropertiesWhite to Off-White SolidUsesA 5-HT3 receptor antagonist. Used as an antiemetic.UsesAzasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.Biological ActivityA selective and potent 5-HT 3 antagonist (K i = 2.9 nM).