TIANFUCHEM--557795-19-4---Sunitinib

 Product Name:SunitinibSynonyms:Sunitinib--- free base;Sunitinib，Sutent;5-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid N-(2-diethylaminoethyl)amide;Suniti;N-[2-(diethylaMino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]Methyl}-2,4-diMethyl-1H-pyrrole-3-carboxaMide;N-[2-DiethylaMino(ethyl-d4)]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxaMide;SU-11248-d4;Sutent-d4CAS:557795-19-4MF:C26H31FN4O6MW:514.55EINECS:Product Categories:Tyrosine Kinase Inhibitors;Pharmaceutical intermediate;API;Isotope Labelled Compounds;SU-11248;Inhibitors;Active Pharmaceutical Ingredients;Sunitinib;Molecular Targeted Antineoplastic;Heterocyclic Compounds;anti-neoplastic;Heterocycles;Intermediates & Fine Chemicals;PharmaceuticalsMol File:557795-19-4.mol
Sunitinib Chemical Properties
Melting point 189-191°Cdensity 1.2Fp 299.8℃pka8.5(at 25℃)CAS DataBase Reference557795-19-4(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
MSDS Information
Sunitinib Usage And Synthesis
Chemical PropertiesYellow SolidUsesA multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). AntineoplasticUsesSunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.UsesSunitinib Malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.UsesLabelled Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK).UsesLabelled Sunitinib, a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK).