Raltitrexed, 98%

Raltitrexed, 98%

Raltitrexed, 98%

Min.Order / FOB Price:Get Latest Price

100 Gram

Negotiable

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

Raltitrexed Raltitrexed 112887-68-0

Quick Details

  • Appearance:White powder
  • Application:Pharmaceutical intermediates
  • PackAge:25KG/drum
  • ProductionCapacity:100|Metric Ton|Week
  • Storage:Room temperature
  • Transportation:BY SEA, AIR OR EXPRESS

Superiority:

The characteristics of raltitrexed
Melting point 176-1800C
Storage conditions Hygroscopic, -20 ° C Freezer, Under Inert Atmosphere
Solubility H2O: ≥10mg / mL
Color off-white to light yellow
InChIKey IVTVGDXNLFLDRM-HNNXBMFYSA-N
CAS Database 112887-68-0 (CAS DataBase Reference)
 
Use and synthesis of raltitrexed
Chemical properties of light yellow powder. Dissolved in water.
Monohydrate: C2lH22N4O6S H2O. Melting point 180-184 ℃.
Use thymidylate synthase inhibitors. For the treatment of colon, rectal cancer.
Use of colon cancer cell lines stronger inhibition
Production method 2,6-dimethyl-4 (3H) -quinazolinone (I) N-alkylated with tert-pentanoyloxymethyl chloride and brominated with N-bromosuccinimide, To give 6- (bromomethyl) -2-methyl-3- [(tert-pentanoyloxy) methyl] -4 (3H) -quinazolinone (III). (m) is condensed with diethyl N- [5-methylaminothiophene-2-carbonyl] -L-glutamate, and the product V and sodium hydroxide aqueous solution are stirred and hydrolyzed at room temperature, The protecting group is then acidified to give the product.

Details:

Henan Tianfu Chemical Co., Ltd is a high-tech enterprise, specializing in pharmaceutical intermediates, located in Zhengzhou High-tech Development Zone. We passed ISO 9001:2008 ub 2009, and won "High-tech Enterprise" by provincial government in 2013. Tianfu specializes in manufacuturing intermediates in areas such as Antitumor, Cardiocascular, central nervous system, diabetes, etc. Tianfu have established an efficient quality control system, owing standardization workshop. Also corportaes with Zhengzhou University, Henan University to establish an innovation practice base to omprove the innovatin ability.
 
Tianfu always adheres to the principle of "Live on High Quality" and puts the customer's interests first. Tianfu products have been exported to Europe and the United States, Japan, Korea, India and Latin America markets. Look forward to the future, Tianfu will keep improving the innovation ability to offer better products and service for more and more customers.

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