Rifamycins sodium properties
Melting point> 215 ° C (dec.)
Storage conditions -20 ° C Freezer
Solubility ethanol: soluble50mg / mL
Soluble in water, alcohol and dimethyl sulfoxide.
Merck 13,8302
Rifamycin sodium use and synthesis method
Chemical properties of orange-red or dark red crystalline powder. The temperature 300 ° C (140 ° C decomposition). Soluble in methanol, ethanol, propanol, ethyl acetate, slightly soluble in water, petroleum ether, dissolved in ether, bicarbonate solution. The aqueous solution is more stable and can be stored at room temperature for 3a. Odorless, bitter taste.
Use broad-spectrum antibiotics, and can enter the cell, is a full-effect bactericide, bactericidal power. Oral malabsorption, for injection only. Mainly used for Gram-positive bacteria such as Staphylococcus aureus, Mycobacterium tuberculosis and other infections caused by Gram-negative bacteria and bile duct and urinary tract infections.
Production methods obtained by fermentation rifamycin S sodium, with vitamin C reduction, and then by the separation operation to get the goods.