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146464-95-1 10-Propargyl-10-deazaaminopterin 98%
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10-Propargyl-10-deazaaminopterin Basic information |
Product Name: | 10-Propargyl-10-deazaaminopterin |
Synonyms: | Pralatrexate;N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid;10-Propargyl-10-deazaaminopterin;L-Glutamic acid, N-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-;Pdx;Unii-A8Q8I19Q20;N-(4-{1-[(2,4-diaMinopteridin-6-yl)Methyl]but-3-yn-1-yl}benzoyl)-L-glutaMic acid;Folotyn |
CAS: | 146464-95-1 |
MF: | C23H23N7O5 |
MW: | 477.47 |
EINECS: | |
Product Categories: | Amino Acids & Derivatives;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 146464-95-1.mol |
10-Propargyl-10-deazaaminopterin Chemical Properties |
Safety Information |
10-Propargyl-10-deazaaminopterin Usage And Synthesis |
Uses | An antifolate with high affinity for the reduced folate carrier-type 1, produces marked complete and durable remissions in a diversity of chemotherapy refractory cases of T-cell lymphoma. |
Definition | ChEBI: A pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. |
10-Propargyl-10-deazaaminopterin Preparation Products And Raw materials |
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