267243-28-7 Canertinib 98%
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Canertinib Basic information |
Product Name: | Canertinib |
Synonyms: | N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]acrylamide;CI-1033(Canertinib);PD-183805;Canertinib base;Canetinib;Canertinib (CI-1033);N-[4-(3-chloro-4-fluoroanilino)-7-(3-Morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-en |
CAS: | 267243-28-7 |
MF: | C24H25ClFN5O3 |
MW: | 485.944 |
EINECS: | |
Product Categories: | Inhibitors |
Mol File: | 267243-28-7.mol |
Canertinib Chemical Properties |
Melting point | 188-190° |
Safety Information |
Canertinib Usage And Synthesis |
Uses | Antineoplastic; irreversible pan-erbB tyrosine kinase inhibitor used to treat cancer. |
Uses | CI-1033 is a potent inhibitor of EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, respectively. |
Definition | ChEBI: A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a propenamido group at the 6-position, and a 3-morpholinopropoxy group at the 7-position. |
Canertinib Preparation Products And Raw materials |
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