| Product Name: | Doxorubicin hydrochloride |
| Synonyms: | ADRIACIN;ADRIBLASTINA;ADRIBLASTINA HYDROCHLORIDE;ADRIAMYCIN HCL;ADRIAMYCIN HYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride;14-HYDROXYDAUNOMYCIN HCL;14-HYDROXYDAUNOMYCIN HYDROCHLORIDE |
| CAS: | 25316-40-9 |
| MF: | C27H30ClNO11 |
| MW: | 579.98 |
| EINECS: | 246-818-3 |
| Product Categories: | APIs;Active Pharmaceutical Ingredients;API;Intermediates & Fine Chemicals;Pharmaceuticals;Antitumour;Adriamycin;inhibitor;Anti-cancer&immunity;Inhibitors |
| Doxorubicin hydrochloride Usage And Synthesis |
| Chemical Properties | Orange-Red Crystalline Solid |
| Usage | Used as an antineoplastic |
| Usage | Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent. |
| Usage | Antibacterial;DNA intercalant |
| Usage | Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently. |
| Usage | Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumor agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently. |
| General Description | Orange-red thin needles. Aqueous solutions yellow-orange at acid pHs, orange-red at neutral pHs, and violet blue over pH 9. |
| Air & Water Reactions | Water soluble. |