Anti Paining Anesthetic Anodyne Powder Articaine Hydrochloride CAS 23964-57-0
Usage:
Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures
In dentistry, articaine is used both for infiltration and block injections, with the block technique yielding the greatest duration of anesthesia
In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine works well.
Applications:
Articaine is a local anaesthetic that has been approved overseas for several years.Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve.This action is prolonged by combining the drug with a vasoconstrictor .
The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.
The Advantages Articaine Hydrochloride:
Characteristic for articaine HCl is that they are fast acting and effective in penetrating bone. The latter has not been proven scientifically but is the opinion of those who work with these products. When using articaine HCl, the patient no longer has to return to the waiting room to allow the anesthetic to take effect. During treatment, it seems as though articaine HCl are more effective than most other anesthetics. For these reasons, increasing numbers of dentists and dental surgeons are opting for articaine HCl.
Articaine Hydrochloride COA:
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Product Name |
Articaine hydrochloride |
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CAS |
23964-57-0 |
Outer Packing |
25kg |
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Production Date |
2016/09/27 |
Shelf life |
2018/09/26 |
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Standard Adopted |
EP 7 |
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Items tested |
Specification |
Result |
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Description |
White or almost white crystalline powder |
White crystalline powder |
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Solubility |
Freely soluble in water and in alcohol |
Complies |
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Identification |
A,B,C,D |
Complies |
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PH |
4.2-5.2 |
4.90 |
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Appearance of solution |
Solution should be clear |
Complies |
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Related substance |
Impurity A ≤0.2%; any other impurity ≤0.1%; Total of other impurities ≤0.5% |
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Heavy metals |
≤5ppm |
<5ppm |
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Loss on drying |
< 0.5% |
0.09% |
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Residue on ignition |
≤0.1% |
0.09% |
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Organic residue |
complies |
complies |
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Assay |
98.5%-101.0% |
99.60% |
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Conclusion |
Qualified |
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