162635-04-3 Temsirolimus

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price: USD 1000.0000

1 Kilogram

FOB Price: USD 1000.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,T/T

Keywords

162635-04-3 Temsirolimus Temsirolimus

Quick Details

Appearance:white powder
Application:pharma
PackAge:as clients needs
ProductionCapacity:1|Metric Ton|Day
Storage:RT
Transportation:sea

Superiority:

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

Our advantage:

1. Higest quality and good package

2.Fast delivery

3.Better payment term

4.Fast response to customer within 6 hours

5.Good business credit in Europe ,US ,Japan ,Korea

Anyway ,if you need any chemicals from China ,Henan Tianfu can help you

Details:

Temsirolimus Chemical Properties

Melting point 99-101°C

density 1.21

Fp 587.8℃

storage temp. -20°C Freezer

solubility Soluble in chloroform, methanol.

color white to off-white

Merck 14,9142

Safety Information

Safety Statements 24/25

RTECS VE6257000

MSDS Information

Temsirolimus Usage And Synthesis

Chemical Properties White Solid

Uses Ester analog of Rapamycin

Uses Temsirolimus (CCI-779) is a specific mTOR inhibitor with IC50 of 1.76 μM.

Uses Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. Like all tacrolimus analogues, temsirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Temsirolimus is extensively cited in the literature with over 700 citations.

Uses Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective acylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. Like all tacrolimus analogues, temsirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Temsirolimus is extensively cited in the literature with over 700 citations.

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