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100 Gram |
Negotiable |
220127-57-1 Imatinib GLIVEC
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Anti-cancer Imatinib mesylate/220127-57-1 Tyrosine-kinase Inhibitor
1. Quick Details:
Product Name: Imatinib Mesylate
Synonyms : GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)
CAS NO.: 220127-57-1
Molecular Formula : C30H35N7O4S
Molecular weight: 589.71
Documents: GMP
Quality: 99%up by HPLC
Usage: Anti tumor drugs
Storage: Preserve in well-closed containers, keep from light and store below 30 °C
2. Product Description:
Chemical name |
Imatinib Mesylate |
|
CAS NO. |
220127-57-1 |
|
Synonyms |
GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3) |
|
Melting point |
183-185°C |
|
Molecular Formula |
C30H35N7O4S |
|
Molecular Weight |
589.71 |
|
Boiling Point |
754.9 °C at 760 mmHg |
|
Flash point |
410.3 °C |
|
Appearance |
Off-white solid |
|
Application |
Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies |
3. Application:
A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)
Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, cKit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib.
4. Specification:
COA
Item |
Acceptance criteria |
Result |
Appearance |
White or almost white powder |
white powder |
Solubility |
Easy to dissolve in the water |
Complies |
Identification |
High-performance liquid chromatograph HPLC |
Almost the same |
Infrared absorption |
Almost the same |
|
Melting point |
222-227°C |
223-224º°C |
Water |
≤0.5% |
0.2% |
Heavy metals |
≤10ppm |
Complies |
Residue on ignition |
≤0.1% |
0.03% |
Related impurity |
Sigle impurity≤0.5% |
0.07% |
Total impurity no more than 1.0% |
0.11% |
|
HPLC assay |
98.0%~102.0% |
99.9% |
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate
4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.
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