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10 Gram |
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99% Loxoprofen sodium Pharmaceutical Raw Materials API Manufacturer
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1. Quick Detail:
English name: Loxoprofen Sodium
Alias: CS-600; Loxoprofen sodium dihydrate; Sodium 2- (4- (2-oxocyclopentylmethyl) phenyl) propionate dihydrate; alpha-Methyl-4 - ((2-oxocyclopentyl) methyl) benzeneacetate sodium salt dihydrate; alpha- methyl-4 - ((2-oxocyclopentyl) methyl) -, sodium salt, dihydrate; sodium 2- {4 - [(2-oxocyclopentyl) methyl] phenyl} propanoate hydrate (1: 1: 2); sodium 2- {4 - [(2-oxocyclopentyl) methyl] phenyl} propanoate; LXP
CAS: 80382-23-6
Formula: C15H17NaO3
MW: 268.2834
Boiling point: 417.9 ° C at 760 mmHg
Flash Point: 220.7 ° C
Vapor Pressure: 9.92E-08mmHg at 25 ° C
Appearance: White powder
Assay:99%
2. Description:
Loxoprofen sodium (CAS 80382-23-6): It is a non-steroidal anti-inflammatory drug which is used for chronic and wet arthritis
The Loxoprofen sodium, with the CAS registry number 80382-23-6, is also known as Benzeneaceticacid, a-methyl-4-[(2-oxocyclopentyl)methyl]-, sodium salt (9CI). It belongs to the product categories of APIS; Aromatics; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals. This chemical's molecular formula is C15H17NaO3 and molecular weight is 268.28. What's more, its systematic name is Sodium 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoate.
3. Specification:
Test Item |
Analysis Specification |
Result |
Description |
It occurs as white to yellowish white crystals or crystalline power |
white crystalline power |
Solubility |
It is very soluble in water and in methanol, freely soluble in ethanol(95), and practically insoluble in diethyl ether |
Meets |
Optical Rotation |
Not show optical rotation |
Meets |
Identification A UV Absorption B. IR Absorption C. Sodium salt |
A: Compare the spectrums between the solution of Loxoprofen Sodium and CRS, both spetra exhibit similar intensities of absorption at the same wavelengths. B: Compare the infrared absorption spectrum of Loxoprofen Sodium with the reference spectrum; both spetra exhibit similar intensities of absorption at the same wavelengths. C: A solution of Loxoprofen Sodium (1~10) responds to the qualitative Tests for sodium salt |
Meets Meets Meets |
pH |
6.5~8.5 |
7.9 |
Clarity and Color of solution |
The solution is clear and colorless or pale yellow. The color is not darker than that of diluted Matching Fluid for Color A(1 in 2) |
Clear and colorless |
Heavy metals |
≤10ppm |
<10ppm |
Related Substances |
The spots other than the principal spot from the sample solution are not intense than the spot from the standard solution. |
Meets |
Water |
11.0~13.0% |
12.0% |
Assay(Dry Basis) |
≥98.5% |
99.9% |
Conclusion |
Complies with requirements of JP15. |
4. Applications:
Used as anti-inflammatory drugs.Loxoprofen sodium is widely used in rheumatoid arthritis, back pain, frozen shoulder, neck and wrist syndrome and other anti-inflammatory analgesic, surgery, trauma and acute analgesic and anti-inflammatory airway inflammation after tooth extraction solution heat analgesic.
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