Ethyl 2-chloro-2-(hydroxyimino)acetate

Details:

1. Introduction of Ethyl 2-chloro-2-(hydroxyimino)acetate (CAS No.:14337-43-0)
With the CAS registry number 14337-43-0, Ethyl Chlorooximidoacetate is also known as 2-Chloro-2-hydroxyiminoacetic acid ethyl ester. This chemical's molecular formula is C₄H₆ClNO₃ and molecular weight is 151.54834. Its IUPAC name is called ethyl (2Z)-2-chloro-2-hydroxyiminoacetate. In addition, Ethyl Chlorooximidoacetate should be sealed and stored at 2-8°C.

2. Properties of Ethyl 2-chloro-2-(hydroxyimino)acetate (CAS No.:14337-43-0)
Density: 1.36 g/cm³
Melting Point: 70-76 °C(lit.)
Boiling Point: 230.5 °C at 760 mmHg
Flash Point: 93.2 °C
Appearance: Brown crystal

3. Structure Descriptors of Ethyl 2-chloro-2-(hydroxyimino)acetate (CAS No.:14337-43-0)
(1)Canonical SMILES: CCOC(=O)C(=NO)Cl
(2)Isomeric SMILES: CCOC(=O)/C(=N/O)/Cl
(3)InChI: InChI=1S/C4H6ClNO3/c1-2-9-4(7)3(5)6-8/h8H,2H2,1H3/b6-3-
(4)InChIKey: UXOLDCOJRAMLTQ-UTCJRWHESA-N

4. Safety Information of Ethyl 2-chloro-2-(hydroxyimino)acetate (CAS No.:14337-43-0)
Hazard Symbols: Xn, Xi
Risk Codes:
41-42/43-36/37/38
Safety Description:
22-26-36/37/39-45

5. Preparation of Ethyl 2-chloro-2-(hydroxyimino)acetate (CAS No.:14337-43-0)
Ethyl 2-chloro-2-(hydroxyimino)acetate can be prepared by glycine ethyl ester; hydrochloride. This reaction will need reagent aq. HCl and NaNO₂. The reaction temperature is -5 °C. The yield is about 54%.


6. Use of Ethyl 2-chloro-2-(hydroxyimino)acetate (CAS No.:14337-43-0)
Ethyl 2-chloro-2-(hydroxyimino)acetate can be used to produce 5-ethoxy-4,5-dihydro-isoxazole-3-carboxylic acid ethyl ester. This reaction will need reagent aq. Na2CO3 and solvent diethyl ether.