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10 Gram |
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99% Exemestane Exemestane Manufacturer Anabolic Steroid Hormones
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Exemestane Anti Estrogen Weight Loss Steroids Aromasin CAS 107868-30-4
Quick Details:
Product name: Exemestane
Alias: Aromasin ; Exemestan;Exemestane
Product Category: Pharmaceutical raw materials and intermediates
Assay: 99%
CAS Registry Number:107868-30-4
Molecular formula: C20H24O2
Appearance: White or Almost White Crystalline Powder
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds
Product Description:
1. Aromasin is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin.
Aromasin is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
2. The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.
3. Aromasin lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
Specifications:
TEST ITEMS | SPECIFICATION | RESULTS |
Description | White Crystalline Powder | White Powder |
Identification | Positive | Positive |
Assay(by HPLC) | 98.0~102.0% | 98.64% |
Absorbance(E1cm) | 465~495 | 482.5 |
Melting Point | 191~195°C | 193.5~195.0°C |
Loss On Drying | 0.5%max | 0.19% |
Specific Rotation | +288°~ +298° | +290.2° |
Residue On Ignition | 0.1%max | 0.03% |
Related Substances | Total:1.5%max | <1.3% |
Single:0.5%max | <0.4% | |
Residue Solvents | 0.2%max | 0.10% |
Heavy Metals | 20PPm max | <10PPm |
Applications:
1. Aromasin was first released on the U.S. market in 2000 after shortly gaining FDA approval a few months prior in 1999. The primary purpose of use as with most AI's would be to combat breast cancer in post-menopausal women. Shortly after, the AI would begin to gain a lot of popularity among anabolic steroid users for its ability to protect against estrogenic related side effects. This action is very similar to the older and more popular AI's in Arimidex and Femara It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI's
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