100 Gram	Negotiable

Min.Order :100 Gram
Purity: 99%
Payment Terms : T/T,

Keywords

25122-46-7 Clobetasol Propionate Corticosteroids Steroid

Quick Details

Appearance:white crystalline powder
Application:Skin Disease
PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
ProductionCapacity:20000|Kilogram|Day
Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

Superiority:

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

Details:

Skin Disease Corticosteroids Steroid Powder Clobetasol Propionate 25122-46-7

Product Description

Clobetasol Propionate

Basic Information:

CAS: 25122-46-7
Molecular formula: C25H32ClFO5
Molecular weight: 466.97
EINECS: 246-634-3
Content: 98.5-102%
Density: 1.28 g/cm3
Melting Point: 195.5-197 °C
Boiling Point: 569 °C at 760 mmHg
Flash Point: 297.9 °C
Specific rotation: +98 - +104 °C
Packing: 1kg/aluminum foil bag
Appearance: white crystalline powder

COA:

Item	Specification	Result
Appearance	White to cream, crystalline powder	White crystalline powder
Identification (by IR)	Conforms to the CRS spectrum	Conforms
Melting Point	Approximately 196 °C	196°C
Specific rotation	+98°~+104°(dried substance)	+99.7°
Loss on drying	≤2.0%	0.2%
Residue on ignition	≤0.1%	0.06%
Heavy metals	≤20ppm	Conforms
Related substance (by HPLC)	Any impurity ≤1.0%	0.22%
	Total impurities ≤2.0%	0.31%
Assay(by HPLC)	Contains 97.0% to 102% of C25H32CIFO5 calculated on dried basis	99.9%
Residual solvents	Ethanol ≤3000ppm	262ppm
	Aceton ≤500ppm	Undetected(LOD 4ppm)
	Pyriding ≤100ppm	Undetected(LOD 3ppm)
	N,N-Dimethylformamide ≤100ppm	Undetected(LOD 10ppm)
Conclusion	Meet the specification according to USP35

Description:

Clobetasol Propionate is a derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.

Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, anti-pruritic, and vasoconstrictive properties. Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, clobetasol propionate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from membrane phospholipids by phospholipase A2.

Clobetasol propionate is a corticosteroid of synthetic steroid used to treat various skin disorders including inflammation, itching, herpes labialis, eczema, psoriasis and lichen sclerosus. Clobetasol propionate is also highly effective for contact dermatitis caused by exposure to poison ivy/oak and auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). Clobetasol propionate is used as first-line treatment for both acute and chronic GVHD of the skin.

Application:

1, clobetasol propionate is a synthetic high topical glucocorticoid drugs. Has a strong anti-inflammatory, anti itching and capillary vascular contraction, the anti-inflammatory effects of hydrocortisone is about 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. At the same time with inhibition of cell mitosis, can effectively penetrate into the skin stratum corneum.

2, external apply to chronic eczema, neurodermatitis, psoriasis and palmoplantar pustulosis, lichen planus, discoid lupus erythematosus, glucocorticoid, topical treatment of pruritic effective and non infectious inflammatory skin disease.

3, has the inhibitory effects of anti-inflammatory, anti allergic, anti proliferation, immune.Can compound products: ketoconazole. Miconazole nitrate, vitamin A acid cream and liniment.

Advantages:

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.

2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.

3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.

4. Warm after-sale service Any of your question would be solved for the first as soon as possible.

Skin Disease Corticosteroids Steroid Powder Clobetasol Propionate 25122-46-7