Genistein

Details:

Standardized Genistein  powder.
Botanical Source:Genista tinctoria Linn, Sophora subprostrala Chun et T.Chen
Appearance: Light yellow crystal powder
Standard Concentrate ratio: NLT98% HPLC
Package: 25/KG per paper drum or packed with little parcel.
Sample/ COA / MSDS are available
Functions;
1. Genistein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, and other legumes. The estimated human normal dietary intake of genistein, primarily as glycosides, is 0 to 0.5 mg/kg. Genistein is present in much greater amounts in nutritional supplements.
2. Genistein is carcinogenic in female neonatal mice, inducing endocrine-dependent uterine tumors in a fashion similar to diethylstilbestrol (DES).
3. Genistein is a tyrosine-specific inhibitor of protein kinase activity, blocking the tyrosine-phosphorylation of histone H2B. In adult animals, dietary genistein has chemopreventive effects on breast, prostate, and other endocrine-dependent tumors.
4. Genistein acts as an antioxidant, similar to many other isoflavones, counteracting damaging effects of free radicals in tissues
5. Genistein protects against pro-inflammatory factor-induced vascular endothelial barrier dysfunction and inhibits leukocyte-endothelium interaction, thereby modulating vascular inflammation, a major event in the pathogenesis of atherosclerosis