Raw Material Losartan Potassium for Antihypertensive CAS 124750-99-8
Basic Info
Losartan potassium
Synonyms: 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL;2-butyl-4-chloro-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-methanol monopotassium salt;2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT;COZAAR;DUP 753;LOSARTAN MONOPOTASSIUM SALT;LOSARTAN POTASSIUM;LOSARTAN POTASSIUM SALT
CAS: 124750-99-8
MF: C22H23ClKN6O
MW: 462.01
- Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) (topical form), allergic rhinitis (such as hay fever) (topical form), asthma (inhalation form)for patients unresponsive to less potent corticosteroids, and penile phimosis. In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone
- Mometasone is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis
- Nasal mometasone is used in adults (including the elderly) and children over 2 years to diminishing the symptoms such as hay fever (seasonal allergic rhinitis) and other allergies (perennial rhinitis), including nasal congestion, discharge, pruritus, and sneezing and to treat nasal polyps.
Losartan potassium------------COA
Items of analysis | Specification | Results |
Characters | White or off white crystalline powder | off white powder |
Solubility | Free soluble in water and methanol, very slightly soluble in chloroform | Conforms |
Infraed absorption | Must similar to reference standard | Conforms |
Ultraviolet absorption | Must similar to reference standard | Conforms |
Test for potassium | Must be positive | positive |
Water | ≤0.5% | 0.20% |
Heavy metals | ≤10ppm | <10ppm |
Single impurity | ≤0.2% | 0.07% |
Total impurity | ≤0.5% | 0.12% |
Isopropyl alcohol | ≤2000ppm | 234ppm |
Assay | 98.5-101% | 99.8% |
Conclusion | Qualified |
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