Raw Material Nifedipine CAS 21829-25-4 for Antihypertensive and Antianginal
Nifedipine
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Nifedipine Basic information |
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Product Name: |
Nifedipine |
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Synonyms: |
1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylicaciddime;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester;4-(2'-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethy;5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-dim;Adalat CC;bay1040;corinfar;Dimethyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate |
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CAS: |
21829-25-4 |
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MF: |
C17H18N2O6 |
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MW: |
346.34 |
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EINECS: |
244-598-3 |
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Product Categories: |
Pharmaceutical;Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Functional Materials;Photopolymerization Initiators;Intermediates & Fine Chemicals;Pharmaceuticals;Calcium channel;Ion Channels;Dihydropyridine;Pharmaceutical intermediate;Isotopically Labeled Pharmaceutical Reference Standard;CAPOTEN;Cardiovascular APIs;Cardiovascular Drugs |
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Mol File: |
21829-25-4.mol |
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Nifedipine Chemical Properties |
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mp |
171-175 °C |
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storage temp. |
2-8°C |
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solubility |
DMSO: soluble |
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form |
powder |
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color |
yellow |
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Water Solubility |
<0.1 g/100 mL at 19.5 ºC |
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Merck |
6528 |
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CAS DataBase Reference |
21829-25-4(CAS DataBase Reference) |
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NIST Chemistry Reference |
Nifedipine(21829-25-4) |
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EPA Substance Registry System |
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-( 2-nitrophenyl)-, dimethyl ester(21829-25-4) |
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Hazard Codes |
Xn,Xi |
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Risk Statements |
22-36/37/38 |
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Safety Statements |
26-36 |
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WGK Germany |
1 |
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RTECS |
US7975000 |
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HazardClass |
IRRITANT |
ProviderLanguage
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Nifedipine |
English |
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SigmaAldrich |
English |
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ACROS |
English |
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Nifedipine Usage And Synthesis |
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Chemical Properties |
Yellow Crystalline Solid |
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Usage |
Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker |
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Usage |
For the management of vasospastic angina, chronic stable angina, hypertension, and Raynaud's phenomenon. May be used as a first line agent for left ventricular hypertrophy and isolated systolic hypertension (long-acting agents). |
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General Description |
Odorless yellow crystals or powder. Tasteless. |
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Air & Water Reactions |
Aqueous solutions are very sensitive to light. . Insoluble in water. |
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Reactivity Profile |
Nifedipine is sensitive to light. |
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Fire Hazard |
Flash point data for Nifedipine are not available; however, Nifedipine is probably combustible. |
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Biological Activity |
L-type calcium channel blocker. |
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Nifedipine Preparation Products And Raw materials |
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Raw materials |
Benzaldehyde-->2-Nitrotoluene-->Methyl acetoacetate-->2-Nitrobenzaldehyde-->4-Aminobenzaldehyde |
Advantages:
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Raw Material Nifedipine CAS 21829-25-4 for Antihypertensive and Antianginal