Manufacture of Candesartan cilexetil intermediates(ethyl esterC6):
TLS pharmaceutical Co., LTD is located at the foot of the World Tourism Attractions Emeishan, which is in the town of Shengli . It situated at the foot of a hill beside a stream , the environment is very beautiful . It posses a registered capital reaching 20 million yuan , covers an area of 20,000 square meters , construction area of 18,000 square meters the total assets amounts to 60 million yuan.After the founding of the company,it depends on the support of government the techniques of academies in Beijing,Shenzhen Sichuan province.TLS aims at the demof the standard market of bulk drugs at home abroad , owns many workshops certified by GMP many pilot workshops fmedicinal intermediates it is equipped with improved public facilities assistant facilities with standard qulity management system (QMS) advanced Quality Control (QC) methods. More important , it cooperates with famous pharmaceutical companies at home abroad , provides excellent quality bulk drugs , key intermediates pilot production technology fthem.
The company's main products: candesartan cilexetil ( CAS No. 145040-37-5 ) intermediates: acid methyl ester compounds ( CAS No. 139481-44-0 ); carboxylic acid ethyl ester compounds ( CAS No.139481-41-7 ); cyclic compounds ( CAS No.139481-69-9 ); candesartan ( CAS No.139481-59-7 ).
Propertise of Candesartan cilexetil intermediates(ethyl esterC6):
(1)ACD/LogP:5.978; (2)# of Rule of 5 Violations:1; (3)ACD/LogD (pH 5.5):5.96; (4)ACD/LogD (pH 7.4):5.98; (5)ACD/BCF (pH 5.5):19605.11; (6)ACD/BCF (pH 7.4):20560.70; (7)ACD/KOC (pH 5.5):40561.43; (8)ACD/KOC (pH 7.4):42538.46; (9)#H bond acceptors:6; (10)#H bond donors:0; (11)#Freely Rotating Bonds:8; (12)Polar Surface Area:77.14
2; (13)Index of Refraction:1.612; (14)Molar Refractivity:124.362 cm
3; (15)Molar Volume:357.541 cm
3; (16)Polarizability:49.301 10
-24 cm
3; (17)Surface Tension:45.5880012512207 dyne/cm; (18)Density:1.19 g/cm
3; (19)Flash Point:339.374 °C; (20)Enthalpy of Vaporization:94.175 kJ/mol; (21)Boiling Point:637.542 °C at 760 mmHg; (22)Vapour Pressure:0 mmHg at 25°C
Specification of Candesartan cilexetil intermediates(ethyl esterC6):
Chinese Name
|
Candesartan cilexetil intermediates ( methyl ester C6 )
|
English Name
|
Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate
|
CAS No.
|
139481-41-7
|
Molecular formula
|
C26H23N3O3
|
View All
-
Address:
Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark
-
Member Since:
2013
-
Business Type:
Manufacturers
-
Tel:
0833-5590788/5590338/5590055
-
Phone:
18784599437
-
Fax:
0833-5590956
-
Email:
postmaster@tlspharm.net
Confirm to collect the product to my collection?
|