1,3,8-Trihydroxy-6-methylanthraquinone 6-Methyl-1,3,8-trihydroxyanthraquinone C.I. 75440; C.I. Natural Yellow 14; Emodin
Physical properties: orange yellow long needle crystal (crystallization in crystallization of orange in the acetone, the methanol is yellow), melting point 256 ℃ ~ 257 ℃. Special reaction with anthraquinone. It is almost insoluble in water, soluble in ethanol and alkaline solution.
Pharmacological effects: emodin can be used as a laxative, although have flooded with activity, but as the susceptible to oxidative damage, the actually in effect is very weak, such as combined with sugar into glycosides, can play a role of flooded with. Rhubarb - 1-o-beta-d-glucoside and rhubarb - 8-o-beta-d-glucoside are the glycosides of the combination of rhubarb and glucose, which are only in different positions and exist in the large yellow. Other antibacterial, cough, anti-tumor, blood pressure and other functions.
Basic introduction:
Physiological activity of emodin decision it not only can be used for medical treatment, also can be used in health care and daily chemicals, such as someone put it used in hair care and skin care products, also someone put it into the natural pigment. Abroad, people use it as a laxative. Pharmacological action:
Anti-tumor activity, anti-microbial growth, immunosuppression, antispasmolysis, cough, diuresis, collapse.
Development progress:
Rhubarb is active, because it is easily oxidized in the body, it is very weak in actual diarrhea, such as the combination of glycosides with sugar, can be used as a function of diarrhea. In addition to the free presence of rhubarb, the reduction status (e.g., the derivatives of anthracol, anthranone) or glycosides with sugar is present. Found in fresh plants, for example, emodin anthracene phenol or emodin anthracene ketone (melting point of 250 ~ 258 ℃), is a product of emodin reduction, such as the long time storage, tend to be oxidized to anthraquinones. Emodin - 1 - O - beta - D - glycosidase melting point is 189 ~ 190 ℃; Emodin - 8 - O - beta - D - glycosidase melting point is 239 ~ 241 ℃, both are the combination of emodin and glucose glycosides, exists in large Huang Zhong at the same time. The former is also one of the active components of the anti-bacterial activity in the staff.
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