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1 Kilogram |
Negotiable |
Granisetron HCl Granisetron 76272-56-5
Test items Quality requirements Results
【Characters】
Apperance White or almost white powder Complies
Solubility Freely soluble in water, sparingly Complies
soluble in methylene chloride,
slightly soluble in methanol. Complies
pH 4.0~6.5 4.6
【Identification】
(a) Infrared absorption spectrophotometry (2.2.24). Complies
Comparison granisetron hydrochloride CRS.
(b) It gives reaction (a) of chlorides(2.3.1). Complies
TESTS
(a) Solution S Dissolve 0.2 g in carbon dioxide free water Complies
R and dilute to 20 ml with the same solvent.
(b)Apperance Solution S is clear (2.2.1) and colourless (2.2.2, Method II). Complies
(d) Relative substances Total ≤1.0% 0.2%
Impurity A≤1.0% Complies
Impurity B≤0.5% Complies
Impurity C≤0.2% Complies
Impurity D≤0.1% Complies
Impurity E≤0.5% Complies
any other impurity≤0.1% Complies
(e)Heavy metals ≤10ppm <10ppm
(f)Sulphated ash ≤0.1% 0.05%
(g)Loss on drying ≤0. 5 % 0.2%
(h) Residual solvents methanol ≤0.3% Complies
Microorganism <100cfu/g Complies
Bacterial endotoxin <9.9eu/mg Complies
Assay 97%-102% 100.6%
HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture.
With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporting pharmaceuticals, veterinary drugs, feed additives, intermediates, fine chemicals, plants extracts, pesticides, food & nutrition additives.
Thinkchem is good at offering excellent outsourcing services to overseas customers as well as laboratory support.
Custom manufacture
Thinkchem is good at offering contract manufacture and custom synthesis under confidential agreement timely and effectively, and providing sales service from grams ,kilograms to multi-tons particularly for pharmaceuticals and their intermediates discovery and development. Thinkchem is equipped with modern lab apparatus including HPLC, GC. TLC AND NMR, motivated by a team of highly qualified personnel using these equipments.
Staff
Thinkchem is composed of chemical technicians, analytical chemists, organic chemists, and chemical engineers educated in leading universities in china. Our staff is supported by a group of consultants from academia with expertise in chemical synthesis and analytical chemistry.
Analytical Items |
Specifications |
Results |
Appearance |
White or slight white crystal |
conforms |
Melting Range |
214℃~217℃ |
215℃~215.8℃ |
Loss on Drying |
not more than 0.5﹪ |
0.14﹪ |
Residue on Ignition |
not more than 0.2% |
0.05﹪ |
2-Methylindazole-3-Carboxylic Acid |
not more than 0.3﹪ |
0.05﹪ |
Related Substances |
Any imputity ≤0.20% Total impurities ≤1.0% |
≤0.07﹪
≤0.7﹪ |
Assay |
not less than 99.0% |
99.4﹪ |
1. Well-trained professional sales team dedicated to source, audit and export.
2. Well-trained R & D team equipped with new knowledge, new ideas and new insights to support product development and innovation.
3. Well-established partnership with major pharmaceutical and chemical companies in china.
4. Wide range of products and efficient regulatory documentation offered to customers.
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