Losartan

Details:

* Losartan Potassium * Therapeutic Category Antihypertensive Agents BP/EP/USP Losartan Potassium Therapeutic Category  Antihypertensive AgentsGrade BP/EP/USPISO 90012008 certified company.GMP certified manufacturing facility. Losartan is an angiotensin-receptor blocker that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system; they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme inhibitors. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.  We offer LOSARTAN POTASSIUM LOSARTAN POTASSIUMWhite to off-white powderOff-white powderFreely soluble in water, soluble in IsopropylAlcohol, slightly soluble in AcetonitrileComplies By IR spectrum of sample as mulls in liquid mineral oil dispersion should concordant with the similar preparation of working standardThe solution 10µg/ml in methanol examine between 20 nm to 400 nm, shows absorption (minimum and maximum) spectra concomitantly obtained for the test solution and the standard solution.It meets the requirements of the test for Potassium Conforms   Conforms   NMT 0.50%w/w0.31NMT 0.001%w/wLess than 0.001  NMT 0.1%NMT 0.2%  Not ApplicableNot ApplicableAny individual imp   NMT 0.20%Total impurities         NMT 0.50%0.120.29NLT 98.50%w/w and NMT 101.00% w/w99.4