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157283-68-6 Travoprost 99%travoprost
Items |
Specifications |
Results |
---|---|---|
Characteristic |
Colorless or pale yellow oil |
Colorless oil |
Identification 1) TLC 2) HPLC |
Conforms Conforms |
Conforms Conforms |
Specific rotation |
[a]20D+52°~+58°(20mg/ml,EtOH,365nm) |
+57.3° |
Water |
N.M.T.1.0% |
0.13% |
Limit of Ethyl acetate |
N.M.T.0.55 |
Not detected |
Purity 1) RelatedSubstances
2) Residual sovents
|
Travoprost acid:N.M.T.0.2% Epoxide derivative:N.M.T.0.4% 15-epi Diastereomer: N.M.T.0.1% 5,6-Trans Travoprost: N.M.T.3.5% 15-Keto derivative: N.M.T.0.3% Any other impurity: N.M.T.0.10% Total impurities: N.M.T.4.0% Acetonitrile: N.M.T.0.04% Ethanol: N.M.T.0.5% n-Hexane: N.M.T.0.05% IPA: N.M.T.0.5% Dichloromethane:0.06% |
0.03% 0.05% Not detected 1.4% Not detected Not detected 1.5% Not detected 0.040% Not detected 0.15% Not detected |
Purity |
NLT 99% |
99.65% |
Assay: |
96.0~102.0%(anhydrous and solvent free basis) |
99.23% |
Items |
Specifications |
Results |
---|---|---|
Characteristic |
Colorless or pale yellow oil |
Colorless oil |
Identification 1) TLC 2) HPLC |
Conforms Conforms |
Conforms Conforms |
Specific rotation |
[a]20D+52°~+58°(20mg/ml,EtOH,365nm) |
+57.3° |
Water |
N.M.T.1.0% |
0.13% |
Limit of Ethyl acetate |
N.M.T.0.55 |
Not detected |
Purity 1) RelatedSubstances
2) Residual sovents
|
Travoprost acid:N.M.T.0.2% Epoxide derivative:N.M.T.0.4% 15-epi Diastereomer: N.M.T.0.1% 5,6-Trans Travoprost: N.M.T.3.5% 15-Keto derivative: N.M.T.0.3% Any other impurity: N.M.T.0.10% Total impurities: N.M.T.4.0% Acetonitrile: N.M.T.0.04% Ethanol: N.M.T.0.5% n-Hexane: N.M.T.0.05% IPA: N.M.T.0.5% Dichloromethane:0.06% |
0.03% 0.05% Not detected 1.4% Not detected Not detected 1.5% Not detected 0.040% Not detected 0.15% Not detected |
Purity |
NLT 99% |
99.65% |
Assay: |
96.0~102.0%(anhydrous and solvent free basis) |
99.23% |
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