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Glutathione(GSH), Reduced form Synonyms 5-L-Glutamyl-L-cysteinylglycine; GSH; gamma-L-Glutamyl-L-cysteinylglycine; y-L-Glu Glutathi…
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Glutathione(GSH), Reduced formSynonyms 5-L-Glutamyl-L-cysteinylglycine; GSH; gamma-L-Glutamyl-L-cysteinylglycine; y-L-Glu Glutathione(GSH), Reduced formSynonyms 5-L-Glutamyl-L-cysteinylglycine; GSH; gamma-L-Glutamyl-L-cysteinylglycine; γ-L-Glutamyl-L-cysteinyl-glycine; GSH; γ-Glu-Cys-GlyCAS NO. 70-18-8EINECS NO. 200-725-4Formula C10H17N3O6SMolecular weight 307.32L(-)-Glutathione, oxidation form Synonyms Glutathione disulfide; GSSG; (γ-Glu-Cys-Gly) (γ-Glu-Cys-Gly) [Disulfide bridge 2a-2b]; Glutathiol CAS NO. 27025-41-8EINECS NO. 248-170-7Formula C20H32N6O12S2Molecular weight 612.63Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anticancer agents.
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