Ep/ USP Minocycline HCl Minocycline Hydrochloride CAS 13614-98-7
Product Description
Minocycline hydrochloride
| Name |
Minocycline hydrochloride |
||
| Product name |
(4S,4aS,5aR,12aR)-9-amino-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrochloride; (4S,4aS,5aR,12aS)-4,7-()-9--3,10,12,12a--1,11--1,4,4abf,5a11,12a--2- |
CAS No. | 149934-21-4 |
| Storage |
Low temperature preservation, preserve in tight containers |
Batch No. | 20170112 |
| Molecular Formula |
C23H27N3O7.HCl |
Purity | 99% |
Minocycline Hydrochloride is a semisynthetic tetracycline class, broad-spectrum antibiotics in the tetracycline class of antibiotics, the product of the strongest antibacterial activity.To gram-positive bacteria including tetracycline resistance of staphylococcus aureus, streptococcus and gram-negative bacteria such as gonorrhea netheril bacteria have a strong role;For chlamydia trachomatis and dissolving urea mycoplasma also has better inhibition.
Minocycline hydrochloride
COA
| Item | Specifications | Results |
| Identification | Complies | Complies |
| Appearance | yellow crystalline powder | Complies |
| Acidity | PH3.5-4.5 | 3.9 |
| Water | 4.3%-8.0% | 6.8% |
| Residue on ignition | Not more than 0.15% | 0.12% |
| Heavy metals | Not more than0.005% | <0.005% |
| Chromatographic purity | ||
| Epi-minocycline | Not more than1.2% | 0.6% |
| Max impurity | Not more than1.2% | 0.6% |
| Total impurities | Not more than2.0% | 0.9% |
| Assay | 890ug/mg-950ug/mg | 905ug/mg |
| Particle sizes | ||
| ≥250ug(60mesh) | Less than 10% | 5% |
| ≥150ug(100mesh) | Less than40% | 23% |
| ≥38ug(400mesh) | Less than50% | 42% |
Minocycline Hydrochloride Application
Minocycline hydrochloride used as vasodilator, Ca channel blocker; Zanarnivir influenza prophylaxis and therapy;dihydropyridine calcium channel blocker.Minocycline hydrochloride is mainly used for clinical urinary tract infections, gastrointestinal infections, gynecological infection, pus eye and ear nose throat disease, skin infection, osteomyelitis.