BP Standard Antifungal Antibiotic (+)-Griseofulvin Powder CAS 126-07-8
Basic views
Product Name |
Griseofulvin |
CAS NO |
126-07-8 |
EINECS |
204-767-4 |
Molecular Formula |
C17H19ClO6 |
Molecular Weight |
354.7822 |
Appearance |
White powder |
Product Description
Griseofulvin (trade names: Gris-peg and Grifulvin V) is an orally administered antifungal drug. It is used both in animals and humans, to treat fungal infections of the skin (commonly known as ringworm) and nail fungus. It was discovered in the culture broth of certain species of the mold Penicillium in 1939.It is produced industrially by fermenting the fungus Penicillium patulum.It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Griseofulvin, an antifungal agent, has been reported to inhibit proliferation of various types of cells. This compound has also been shown to strongly suppress the dynamic instability of individual microtubules via reduction of the rate and extent of the growing and shortening phases. The effects that Griseofulvin has on microtubules can cause mitotic arrest and abnormalities, such as multipolar spindles, misaligned chromosomes, and fragmented nuclei
Commerce clause
Minimum order quantity |
Negotiate |
Price |
Negotiate |
Packaging Details |
1kg/aluminium foil bag or as required |
Delivery time |
Within 24 hours upon receipt of payment |
Payment Terms |
, MoneyGram, T/T, Bitcoin,Bamktransfer ect. |
Supply Ability: |
50kg/month |
(+)-Griseofulvin COA
Test Items |
Specification |
Test Results |
Characteristics |
A yellowish-white,microfine powder |
yellowish-white,microfine powder |
Melting point |
220ºC About 220ºC |
218.4ºC-219.4ºC |
Specific optical rotation |
+354o~+364o |
+356o |
Identification |
Meets the requirements |
Meets the requirements |
Check-up Particles size |
Meets the requirements |
Meets the requirements |
Acidity |
0.25g consumed 0.02mol/l NaOH not more intensely coloured than reference solution Y4 |
0.6ml |
Clarity and colour of solution |
The solution is clear and not more intensely coloured than reference solution Y4 |
Y5~Y6 |
Matter soluble in petroleum spirit |
≤0.2% |
0.1% |
Sulphated ash |
≤0.2% |
0.1% |
Related substances |
-Cl:<0.60 -H<0.15 |
-Cl:0.48-H:0.04 |
Loss on drying |
≤1.0% |
0.1% |
Abnormal toxicity |
Meets the requirements |
Meets the requirements |
assay(on the anhydrous substance) |
97.0%~102.0% |
98.3% |
Conclusion |
The above certificate of analysis is in compliance with BP/EP,meets the standard requirements. |