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Pharmaceutical Raw Materials Azithromycin CAS 83905-01-5 For Sensitive Bacterial Infections

Pharmaceutical Raw Materials Azithromycin CAS 83905-01-5 For Sensitive Bacterial Infections

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100 Gram

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  • Min.Order :100 Gram
  • Purity: 99%
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Keywords

83905-01-5 Azithromycin 9-Deoxo-9a-methyl-9a-aza-homoerythromycin

Quick Details

  • Appearance:White crystalline powder
  • Application:Acute otitis media caused by H. influenzae, M. catarrhalis or S. pneumoniae
  • PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
  • ProductionCapacity:20000|Kilogram|Day
  • Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
  • Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

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1. Guaranteed purity;

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Details:

Pharmaceutical Raw Materials Azithromycin CAS 83905-01-5 For Sensitive Bacterial Infections, respiratory infection

 

 

 

Details:

Product name: Azithromycin

Alias: 9-Deoxo-9a-methyl-9a-aza-homoerythromycin A;11-(4-Dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-2-ethyl-3,4,10-tr

CAS NO.: 83905-01-5

MF: C38H72N2O12

MW: 748.99

MS:

Pharmaceutical Raw Materials Azithromycin CAS 83905-01-5 For Sensitive Bacterial Infections

 

Melting Point: 113-115ºC

Appearance: White crystalline powder

Grade: Pharmaceutical Grade & Veterinary Grade

Storage: Closed, shading preservation

Usage: Antibiotics used for a variety of sensitive bacterial infections, such as respiratory infection; skin and soft tissue infection.

 

 

 

Description:

 

Azithromycin (trade names Zithromax, Azyth, Sumamed) is an antibiotic useful for the treatment of bacterial infections. It is an azalide, a subclass of macrolide antibiotic. It is derived from erythromycin, with a methyl-substituted nitrogen atom incorporated into the lactone ring, thus making the lactone ring 15-membered. Azithromycin is somewhat more potent against certain bacterial species than erythromycin, but its widespread popularity arises primarily from its slow elimination from the body, which allows many infections to be treated with 3-5 days of once-daily administration, compared to 3-4 times a day for up to two weeks for erythromycin.

 

Azithromycin inhibits the growth of bacteria by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. This mechanism of action is typical of macrolide antibiotics.

 

This antibiotic is widely used alone or in combination with other drugs to treat otitis media, pharyngitis, community-acquired respiratory infections (including pneumonia), gastrointestinal infections (such as those caused by eating contaminated food), and gonorrhea.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.

 

Applications

Azithromycin is used to treat many different infections, including:
Acute bacterial exacerbations of chronic obstructive pulmonary disease due to H. influenzae, M. catarrhalis, or S. pneumoniae
Acute bacterial sinusitis due to H. influenzae, M. catarrhalis, or S. pneumoniae
Community-acquired pneumonia' due to C. pneumoniae, H. influenzae, M. pneumoniae, or S. pneumoniae
Acute otitis media caused by H. influenzae, M. catarrhalis or S. pneumoniae
Pharyngitis or tonsillitis caused by S. pyogenes as an alternative to first-line therapy in individuals who cannot use first-line therapy
Uncomplicated skin and skin structure infections due to S. aureus, S. pyogenes, or S. agalactiae
Urethritis and cervicitis due to C. trachomatis or N. gonorrhoeae
Genital ulcer disease (chancroid) in men due to H. ducreyi

 

 

Specification

 

 

USP26 Standard:

 

Test Item

Analysis Specification

Result

Description

White or almost white crystalline powder, No odor and bitter. Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride.

Conforms

Identification

A: IR: Conforms to the Azithromycin RS spectrum

B: HPLC: The retention time of azithromycin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Conforms

Conforms

Specific rotation

-45°~-49°(Anhydrous substance 20mg/ml dehydrated alcohol)

-47°

Crystallinity

Meets the requirements

Conforms

pH

9.0~11.0 ( 0.1g /50ml methanol-water (1:1))

10.0

Water

4.0%~5.0%

4.4%

Residue on Ignition

≤0.3%

0.02%

Heavy metals

≤0.0025%

<0.0025%

Residual solvents

Methylene Chloride≤600ppm

Acetone≤5000ppm

Not detected

1159.0ppm

Assay((HPLC)

945~1030 μg /mg ( Anhydrous substance)

965μg /mg

Conclusion

Conform to USP 26 Standard

 

 

USP36 Standard:

 

Item

Standard

Result

Characters

White crystallinity powder

Complies

Identification

a) Infrared Absorption

Complies

b) HPLC

Complies

Specific rotation

-45°~ -49°

-47°

Crystallinity

Meets the requirements

Complies

pH

9.0~11.0

10.3

Water

4.0~5.0%

4.3%

Residue on ignition

≤0.3%

0.07%

Heavy metals

≤25%

less than0.0025%

Assay

945~1030μg/mg (C38H72N2O12)Based on anhydrous substance

 

Advantages:
 
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.


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Pharmaceutical Raw Materials Azithromycin CAS 83905-01-5 For Sensitive Bacterial Infections, respiratory infection

 

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