Active Pharma Ingredients Telmisartan CAS 144701-48-4 for hypertension Treatment
Basic info:
Product Name:Telmisartan
Chemical name: 4'-[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1ylmithyl]-2-carboxylic acid
CAS: 144701-48-4
Molecular formula: C33H30N4O2
Molecular weight: 514. 62
Character: White or off-white crystalline powder;odourless bitterness
Sulphate: =<0.05%
Chloride: =< 0.01%
Related substance =< 1.0%
Dichlormethane: =< 0.06%
Chloroform: =< 0.006%
Methanol: =< 0.01%
Residue on ignition: =< 0.1%
Ultimate analysis: C 77. 02%,H 5. 88%,N 10. 89%,O 6. 22%
| Product name | Telmisartan |
| Synonyms | TU-199;TELMISARTAN;PRITOR;MICARDIS;BIBR 277;4'[(1,4'-DIMETHYL-2'-PROPYL[2,6'-BI-1H-BENZIMIDAZOL]-1'-YL)METHYL][1,1'-BIPHENYL]-2-CARBOXYLIC ACID;4'-[(1,4'-DIMETHYL-2'-PROPYL[2,6'-BI-H-BENZIMIDAZOL]-1'-YL)METHYL][1,1'-BIPHENYL]-2-CARBOXYLIC ACID;3-methoxy-8-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl sulfinyl]-2,7,9-triazabicyclo[4.3.0]nona-2,4,8,10-tetraene |
| CAS NO | 144701-48-4 |
| MF | C33H30N4O2 |
| MW | 514.63 |
| Appearance | White or off white crystalline powder |
| Assay | 99%min |
| Storage | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Brand Name | NJBN STEROID |
| Delivery | EMS, DHL, TNT, FedEx, UPS |
| Delivery time | within 24 hours upon receipt of payment |
| Product Category | Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;INTERMEDIATESOF;Antihypertensive;Imidazoles;(intermediates of telmisartan);Telmisartan;Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Other Products;Hypertension.;CARADRIN |
| Usage | It can be used as anti-hypertensive drugs and vasodilator hormone antagonist. |
Product Description:
1.Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand).
Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on muscle cells of blood vessels. Angiotensin's attachment to the receptors causes muscle cells to shorten and narrow the blood vessels (vasoconstrict), which leads to an increase in blood pressure (hypertension). Telmisartan blocks the angiotensin receptor. By blocking the action of angiotensin, telmisartan widens blood vessels (vasodilate) and reduces blood pressure. Telmisartan was approved by the FDA in November 2000.
2.Telmisartan is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.Telmisartan is also used to lower the risk of heart attacks or stroke in patients 55 years of age and older who have diabetes or heart problems.Telmisartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, telmisartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Application:
Telmisartan is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Telmisartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so blood can flow more easily.
Telmisartan is a new antihypertensive drugs, a specific angiotensin receptor (AT1 type) antagonist. Telmisartan alternative angiotensin receptor binding with high affinity AT1 receptor subtype. Telmisartan AT1 receptor sites in any part of agonist effects of telmisartan in combination with selective AT1 receptors, the binding lasting effect. Buck stability does not cause coughing.
Telmisartan can be useful for moderating blood pressure of those with elevated blood pressure, both when using anabolic steroids and when not doing so, and also can improve endurance, aid fat loss, and potentially may improve long term health.
Advantages:
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