Inhibitor Powder / Inhibitor CAS No.: 461432-26-8 Purity 99% Dapagliflozin for Antivirals
| Name | Dapagliflozin |
| Synonyms | (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol |
| Molecular Formula | C21H25ClO6 |
| Molecular Weight | 408.87 |
| CAS Registry Number | 461432-26-8 |
Certificate of Analysis
| Tests | Specifications | Results |
| Appearance | White or off-white powder | White powder |
| Identification: | ||
| A. IR(KBr) | The sample spectrum corresponds to that of the working standard | Confirm |
| B. HPLC | The retention time of the major peak in the chromatogram of the sample corresponds to that exhibited by the working standard | Confirm |
| Single impurity | Not more than 0.1% | 0.08% |
| Total impurities | Not more than 1.0% | 0.5% |
| E.e % | More than 98.5% | 99% |
| Assay (by HPLC) | Not less than 98.0% and not more than 102.0% w/w | 99.1% |
| Conclusion | Comply with In-house standard. | |
| Storage | Store protected from light and moisture | |
Dapagliflozin(BMS512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) is in development for the treatment of type 2 diabetes mellitus (T2DM).
Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine.
Advantages:
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Inhibitor Powder / Inhibitor CAS No.: 461432-26-8 Purity 99% Dapagliflozin for Antivirals