Antihistaminic Pharmaceutical White Powder CAS 90729-43-4 Ebastine
Description:
| Product Name | Ebastine |
| Synonyms: | 4-(4-benzhydryloxy-1-piperidyl)-1-(4-tert-butylphenyl)butan-1-one;EBASTEL;EBASTIN;EBASTINE;EVASTEL;KESTINE;1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-buta;1-butanone,1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidiny |
| MF | C32H39NO2 |
| MW | 469.66 |
| CAS NO | 90729-43-4 |
| Molecular structure |
|
| Density | 1.09g/m3 |
| Melt point | 80-82°C |
| Boiling point | 596.3°C at 760 mmHg |
| Flash point | 314.5°C |
| Vapour Pressure | 3.47E-14mmHg at 25°C |
Ebastine (trade names Evastin, Kestine, Ebastel, Aleva, Ebatrol) is a H1 antihistamine with low potential for causing drowsiness.
It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of theH1 receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness.
Function:
Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathicurticaria. It is available in 10 and 20 mg tablets and as fast-dissolving tablets,as well as in pediatric syrup. It has a recommended flexible daily dose of 10 or 20 mg, depending on disease severity.
In accordance with the basting with cetirizine hydrochloride, loratadine, cetirizine left-handed, imidazole westin is the commonly used several without sedating antihistamines H1 receptor resistance, drug allergy, its characteristic is on the central nervous without sedation or sedation is very small, antihistamines effect is stronger, can significantly inhibited by histamine.
Application:
Clinical main treatment of various allergic diseases such as chronic idiopathic urticaria, seasonal and perennial allergic rhinitis, itchy skin disease. Adult patients with chronic urticaria and allergic rhinitis
Specification:
| Items | Specification | Results |
| Characteristics | White crystalline powder | Conforms |
| Odor | odorless | Conforms |
| Identification | IR spectrum | Conforms |
| Assay(HPLC) ,% | ≥99.5 | 99.7 |
| Individual impurities(%) | ≤0.1 | 0.09 |
| Melting point(℃) | 84.0~87.0 | 84.8~85.8 |
| Loss on drying(%) | ≤0.5 | 0.1 |
| Residue of ignition(%) | ≤0.1 | 0.05 |
| Heavy Metal | 10ppm maximum | Conforms |
| Lead | 2ppm maximum | Conforms |
| Arsenic | 2ppm maximum | Conforms |
| Mercury | 1ppm maximum | Conforms |
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
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