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25322-68-3 Proethylene glycol PEG-400
Wuhan Fortuna Chemical Co.,Ltd is a professional integrative chemical enterprise with 18 years exporting experience,which is being engaged in Pharmaceutical and its intermediates, Food and Feed additives, Fine chemicals.
Polyethylene Glycol (PEG) is a synthetic, water-soluble polymer composed of repeating ethylene oxide units (?(CH?CH?O)??). Key aspects include:
Versatile Solubility: Miscible with water and organic solvents.
Non-Toxic & Biocompatible: Widely used in medical and consumer products.
Molecular Weight Variability: Ranges from liquids (low MW, e.g., PEG 400) to solids (high MW, e.g., PEG 20,000).
Pharmaceuticals:
Laxatives: PEG 3350 for bowel preparation.
Drug Delivery: Enhances solubility/stability of medications; key in mRNA vaccines (e.g., COVID-19 lipid nanoparticles).
Excipient: Binder in tablets and ointments.
Cosmetics: Moisturizer in creams/lotions.
Industry: Lubricant, antifoaming agent, or binder in manufacturing.
Biotech: PEGylation modifies proteins/nanoparticles to prolong circulation.
Generally recognized as safe (FDA-approved), but rare allergic reactions or impurities (e.g., ethylene oxide residuals) may occur.
Biodegradable under specific conditions.
Summary: PEG’s adaptability makes it indispensable in medicine, cosmetics, and industry, balancing efficacy with low toxicity.
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