Active Pharmaceutical Intermediates powder Tretinoin CAS 302-79-4 to Treat Acne
Quick detial :
| Product name | Tretinoin |
| Other name | ALL-TRANS;RETINOIC ACID;RETINOIC ACID, ALL TRANS |
| CAS | 302-79-4 |
| MF | C20H28O2 |
| MW; | 300.44 |
| Molecular structure |
|
| Assay | 99% |
| Appearance: | Yellow-Orange Powder |
| Usage | keratolytic, antiacne, antineoplastic |
Description
1). Tretinoin is commonly used in dermatology drugs, which is the department of vitamin A (Victoria methanol) metabolic intermediates.It mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal.
2). Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain therapeutic effect, treat a variety of skin diseases. The use of the drug can penetrate topical skin quickly, enable significantly increased epithelial cell turnover. This class of drugs has strong and rapid inhibition on the secretion of the sebaceous glands, can reduce sebum secretion. In addition, the product also has anti-tumor, promote wound healing and anti-inflammatory effects.
3). It is a yellow needle crystal, with a similar smell of vitamin acetate. Soluble in methanol, ethanol, acetone, also in vegetable oil and fatty. In case of light, it is thermal instability, suck up moisture in the air, polymerization and metamorphism in water. The melting point of all trans-vitamin A acid is 182 ~ 180°C, the melting range of which is mixed with a small amount of isomers is 170 ~ 190°C.
4). This product can induce epidermal hyperplasia, and improve the granular layer and the cell layer thickness.It can influence the silk protein process and the formation of cross-linked film and promote the differentiation of epidermal granular layer cells in the late stage of the differentiation of the epidermal cells by affecting K10, K1 keratin solution.
Specification;
| Items | Specifications | Results |
| Appearance | Yellow crystalline powder | Complies |
| Identification | The infrared absorption is same as referance | Complies |
| Should exhibits maximum absorption at 352nm | Complies | |
| Limits of isotretinoin | ≤5.0% | 0.41% |
| Loss on drying | ≤0.5% | 0.03% |
| Heavy metals | ≤0.002% | <0.002% |
| Residue on ignition | ≤0.1% | 0.03% |
| Assay(on dried basis) | 98.0%~102.0% | 100.5% |
Function
1). Used for usual acne, lichen planus, white spot, hair red pityriasis and facial pityriasis simplex
2). Also can be used as an auxiliary therapy for psoriasis.
3). Can also be used in the treatment of multiple verruca vulgaris, and abnormal keratinization of various skin
diseases such as ichthyosis, hair follicle keratinization disorder
4). For cancer prevention and treatment of precancerous lesions, Such as white spot of the oral mucosa, laryngeal papilloma, stunting disease
5). Used for skin malignant tumor such as squamous cell carcinomas and basal cell carcinoma, mycosis enzyme disease
6). For acute early young granulocyte leukemia.
Medical Usage
1). Tretinoin can increase the cell nucleus division and epidermal cell turnover, form of the stratum corneum cell adhesion, and easy to fall off. It can remove the existing acne, while inhibiting the formation of new acne, hair follicle epithelial replacement can prevent the blockage of the plug. The synthesis of keratin is also inhibited, which can affect the metabolism of epithelial cells. It has the effect of promoting the proliferation and differentiation of epithelial cells, and the dissolution of keratinocytes.
2). It is used in the treatment of acne vulgaris, especially the blackhead acne lesions, senile, fluorescent or drug skin atrophy, ichthyosis and various abnormal keratinization and pigment excessive calm skin disease, and psoriasis.
Application
(1) Applies to abnormal tyshiyongyupe of acne, fish phosphorus disease and abnormal psoriasis.
(2) Resistance to abnormal skin drugs.
(3) Tretinoin mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal. Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain therapeutic effect, treat a variety of skin diseases. Tretinoin is mainly used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus, impetigo, vitiligo, lichen psoriasis, the face of pityriasis alba, etc.
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.
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Active Pharmaceutical Intermediates powder Tretinoin CAS 302-79-4 to Treat Acne