Top Antimuscarinic Treatment CAS 654671-77-9 Sitagliptin Phosphate Monohydrate Chemical
Sitagliptin Phosphate Monohydrate-------------------Basic Information
| Product Name | Sitagliptin phosphate monohydrate |
| CAS | 654671-77-9 |
| MF | C16H20F6N5O6P |
| MW | 523.3240802 |
| Product Categories | API;Inhibitor;Inhibitors |
| Chemical Properties | white crystalline |
| Usage | antimuscarinic . |
Sitagliptin Phosphate Monohydrate-------------------Description
Sitagliptin is a white to off-white, crystalline, non-hygroscopic powder. It is soluble in water and N,N-dimethyl formamide; slightly soluble in methanol; very slightly soluble in ethanol, acetone, and acetonitrile; and insoluble in isopropanol and isopropyl acetate.
Each film-coated tablet of JANUVIA contains 32.13, 64.25, or 128.5 mg of sitagliptin phosphate monohydrate, which is equivalent to 25, 50, or 100 mg, respectively, of free base and the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, and sodium stearyl fumarate. In addition, the film coating contains the following inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, red iron oxide, and yellow iron oxide.
Sitagliptin Phosphate Monohydrate-------------------Application
Sitagliptin Phosphate is the phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis
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