18449-41-7 Madecassic acid 98%
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Madecassic acid Basic information |
Product Name: | Madecassic acid |
Synonyms: | 6BETA-HYDROXYASIATIC ACID;(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid;MADECASSIC ACID;Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-;(1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid;Hydroxy asiaticoside;MADECASSIC ACID(P);2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid |
CAS: | 18449-41-7 |
MF: | C30H48O6 |
MW: | 504.7 |
EINECS: | |
Product Categories: | Miscellaneous Natural Products;The group of Asiaticoside;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Cofactor;Inhibitors |
Mol File: | 18449-41-7.mol |
Madecassic acid Chemical Properties |
Melting point | 270°C (dec.) |
Madecassic acid Usage And Synthesis |
Chemical Properties | White powder |
Uses | wound healing |
Uses | Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities. |
Definition | ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3, 6 and 23 (the 2alpha,3beta,6beta stereoisomer). |
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