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Details:
Product Name:FleroxacinSynonyms:6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacid;AM-833, Ro-23-6240, Megalocin, Megalone, Quinodis, 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid;AM-833, Megalocin, Megalone, 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid, 6,8-Difluoro-1-(2-fluoroethyl)1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxo-7-(4-methyl-1-piperazinyl)quinoline-3-carboxylic acid;6,8-difluoro-1-(2-fluoroethyl)-4-keto-7-(4-methylpiperazin-1-yl)quinoline-3-carboxylic acid;6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid;6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid MegaloneCAS:79660-72-3MF:C17H18F3N3O3MW:369.34EINECS:Product Categories:Antibiotics for Research and Experimental Use;Biochemistry;Quinolones (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals;Quinodis, MegalocinMol File:79660-72-3.mol
Fleroxacin Chemical Properties
Melting point 264-266°Cstorage temp. 2-8°Csolubility 0.1 M NaOH: soluble10mg/mLcolor white to off-whiteMerck 14,4099CAS DataBase Reference79660-72-3(CAS DataBase Reference)
Safety Information
RTECS VB1999050
MSDS Information
Fleroxacin Usage And Synthesis
Chemical PropertiesWhite Needle-Like CrystalsUsesantibioticUsesAn antibacterialDefinitionChEBI: A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-n gative bacteria.
Fleroxacin Preparation Products And Raw materials
Raw materialsEtanol-->Potassium carbonate-->Acetic anhydride-->Diethyl ethoxymethylenemalonate -->1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester-->QUINOLINE-3-CARBOXYLIC ACID-->2,3,4-Trifluorobenzenamine