Newblue CHEM-- pris...

Newblue CHEM--	pristimerin

Newblue CHEM-- pristimerin

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Keywords

1258-84-0 pristimerin pristimerin

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Details:

Product Name: pristimerin
Synonyms: pristimerin;3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid methyl ester;Celastrol-methylether;(9b,13a,14b,20a)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tertraen-29-oic acid methyl ester;(9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oicacidmethylester;3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, methyl ester;Celastrol methyl ester;Pristimerin(NSC 99281)
CAS: 1258-84-0
MF: C30H40O4
MW: 464.642
EINECS:  
Product Categories:  
Mol File: 1258-84-0.mol
pristimerin Structure
 
pristimerin Chemical Properties
storage temp.  Store at -20°C
solubility  DMSO: ≥5mg/mL
color  orange
 
Safety Information
MSDS Information
 
 
pristimerin Usage And Synthesis
Uses antineoplastic, antiinflammatory
Uses Pristimerin is a triterpenoid that inhibits tumor angiogenesis by targeting VEGFR2 activation and is known to exhibit anti-inflammatory properties.
Biological Activity Potent and reversible inhibitor of monoacylglycerol lipase (MGL) (IC 50 = 93 nM). Also suppresses NF- κ B activation via inhibition of proteasome chymotrypsin-like activity and IKK α / β . Displays antitumor, anti-inflammatory and antimicrobial activities.

 

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