Pharmaceutical Raw Powder Loratadine CAS 79794-75-5 for Allergy

Pharmaceutical Raw Powder Loratadine CAS 79794-75-5 for Allergy

Product name:    Loratadine
Other Name:    LORATADINE;LORATADINE-D5;ethyl 4-(8-chloro-5,6-dihydro-11h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate;4(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLATE;4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER;
CAS:79794-75-5
Molecular formula:C22H23ClN2O2
MW:382.88
Purity:99%
Appearance:White crystal powder



Loratadine Description:
 
Loratadine, is a long-acting, non-sedating antihistamine that is used for the treatment of allergies. Histamine is a chemical that causes many of the signs and symptoms of an allergy. Histamine is released from histamine-storing cells (mast cells) and attaches to other cells that have receptors for histamine on their surfaces. Histamine stimulates the cells to release chemicals that produce effects that we associate with allergy, including welts, itching, and tissue swelling. Loratadine(Claritin) blocks one type of histamine receptor (the H1 receptor) and thus prevents activation of cells with H1 receptors by histamine.
 
Application of of Active Pharmaceutical Ingredients Reserpine:
 
1.Antihistamines, peripheral nerves are highly selective H1-receptor, the role of strong, long time. For allergic arthritis, allergic rhinitis.
2. National second-class anti-allergy drugs, for the relief of seasonal allergic rhinitis nasal and non-nasal symptoms and relieve chronic urticaria.

Medical Usage of  Loratadine:

Loratadine is indicated for the symptomatic relief of allergy such as hay fever (allergic rhinitis), urticaria (hives), chronic idiopathic urticaria, and other skin allergies. For allergic rhinitis (hay fever), loratadine is effective for both nasal and eye symptoms: sneezing, runny nose, itchy or burning eyes.
Similarly to cetirizine, loratadine attenuates the itching associated with Kimura's disease. It is marketed for its less sedating properties.
 
Loratadine Antiallergic:
 
Loratadine is a common antiallergic medication, which is a second generation long-acting tricyclic antihistamine, rapid onset of action is strong, does not contain hormones, absorbed by the body metabolism with more active desloratadine, inhibiting histamine H1 receptor by competitively inhibit histamine-induced allergic symptoms, with no obvious anticholinergic and central inhibition. It is used for the relief of clinical symptoms of allergic rhinitis related, such as sneezing, runny nose and nasal itching, eye itching and burning. It is also used to relieve symptoms of chronic urticaria and other allergic skin diseases.