C20H18O5 DEMETHOX...

C20H18O5   DEMETHOXYCURCUMIN  22608-11-3

C20H18O5 DEMETHOXYCURCUMIN 22608-11-3

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DEMETHOXYCURCUMIN 22608-11-3 C20H18O5

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  • Appearance:Powder
  • Application:22608-11-3
  • PackAge:Aluminium Foil Bag and Paper Drum
  • ProductionCapacity:100|Metric Ton|Day
  • Storage:1MT
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Details:

DEMETHOXYCURCUMIN Basic information
Product Name: DEMETHOXYCURCUMIN
Synonyms: Feruloyl-P-hydroxycinnnamoylmethane;Demethoxycurcumin;1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione;1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-;MonodeMethoxycurcuMin;(1E,6E)-1-(4-Hydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-d;(E,E)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione;1-(4-Hydroxy-3-Methoxyphenyl)-7-(p-hydroxyphenyl)-1,6-heptadiene-3,5-dione
CAS: 22608-11-3
MF: C20H18O5
MW: 338.35
EINECS:  
Product Categories: Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 22608-11-3.mol
DEMETHOXYCURCUMIN Structure
 
DEMETHOXYCURCUMIN Chemical Properties
storage temp.  2-8°C
solubility  DMSO: ≥10mg/mL
color  orange
 
Safety Information
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
HS Code  29145090
MSDS Information
 
 
DEMETHOXYCURCUMIN Usage And Synthesis
Uses The demethoxy derivative of Curcumin (C838500) that regulates anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. It attenuates the Wnt/β-catenin pathway through do wn-regulation of the transcriptional coactivator p300.
Uses Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin. More stable than curcumin in physiological media, DMC suppresses proliferation in cancer cells at 50-100 μM. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits lipopolysaccharide induction of iNOS.

 

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