Pharmaceutical Raw Powder CAS 2068-78-2 Vincristine Sulfate for Anti-Cancer Treatment
Quick Detail:
| Product Name | Vincristine sulfate |
| Synonyms | VINCRISTINE SULFATE;VINCRISTINE SULFATE, APOCYNACEAE SPECIES;VINCRISTINE SULFATE SALT;VINCRISTINE SULPHATE;VCR;VCR, LEUKOCRISTINE SULFATE;VCR SULFATE;22-oxo-vincaleukoblastinsulfate(1:1)(salt) |
| CAS NO | 2068-78-2 |
| Einecs No | 246-634-3 |
| MF | C46H58N4O14S |
| MW | 923.04 |
| EINECS: | 218-190-0 |
| Purity | >99% |
| Chemical Properties | Crystalline Solid |
| Product Categories | Pharmaceutical Intermediates;Heterocycles;Miscellaneous Reagents |
| Lead time | Within 24 hours upon receipt of payment |
| Shipment | EMS, DHL, TNT, FedEx, UPS |
| Uses | An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. |
| Product Categories | Organics;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pharmaceutical intermediate;TORADOL;Hormone Drugs |
Description:
Vincristine Sulfate is the sulfate salt of a natural alkaloid isolated from the plant Catharanthus roseus (Vinca rosea L.) with antimitotic and antineoplastic activities. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca(2+)-activated ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
Application:
Vincristine sulfate is approved to treat:
- Acute leukemia.
Vincristine sulfate is sometimes used to treat other types of cancer, including:
- Hodgkin lymphoma.
- Neuroblastoma.
- Non-Hodgkin lymphoma (NHL).
- Rhabdomyosarcoma.
- Wilms tumor.
Vincristine sulfate is also being studied in the treatment of other types of cancer.
Advantages:
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