TIANFU CHEM-- Mitig...

TIANFU CHEM-- Mitiglinide calcium

TIANFU CHEM-- Mitiglinide calcium

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Keywords

145525-41-3 Mitiglinide calcium Mitiglinide calcium

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Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

 

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Details:

 
Product Name: Mitiglinide calcium
Synonyms: MITIGLINIDE CALCIUM HYDRATE;calcium 2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionate;(as,3ar,7as)-octahydro-gamma-oxo-alpha-(phenylmethyl)-2h-isoindole-2-butanoic acid calcium salt dihydrate;Monocalcium bis[(2S)-2-benzyl-3-(cis-hexahydro isoindolin -2-carbonyl)propionate]dihydrate;MITIGLINIDECALCIUM(FORR&DONLY);MITIGLINIDE KAD-1229;Mitiglinide calcium;Mitiglinide calcium anhydrous
CAS: 145525-41-3
MF: (C19H24NO3)2.Ca
MW: 668.88
EINECS:
Product Categories: Pharmaceutical material and intermeidates;API;White crystal posder;Inhibitors
Mol File: 145525-41-3.mol
Mitiglinide calcium Structure
Mitiglinide calcium Chemical Properties
Melting point 146-148°C
density 1.175
storage temp. room temp
solubility DMSO: ≥10mg/mL at warmed to 60°C
color white to beige
CAS DataBase Reference 145525-41-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 36
MSDS Information
Mitiglinide calcium Usage And Synthesis
Description Mitiglinide is the calcium salt form of Mitiglinide, which is a drug for the treatment of type II diabetes. It belongs to the meglitinide class blood glucose-lowering drug. Its mechanism of action is through stimulating the insulin secretion through closing the ATP-sensitive potassium channels in the pancreatic beta-cells. This process leads to depolarization, further stimulating the influx of calcium through the voltage-gated calcium channels. The high intracellular calcium level results in the exocytosis of insulin granules, alleviating the symptoms of type II diabetes.
References #
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Uses Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells

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