top Finasteride

top Finasteride

top Finasteride

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price: USD 1.0000

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

Finasteride high purity Finasteride factory supply Finasteride

Quick Details

  • Appearance:Colorless to light yellow liquid
  • Application:Used in a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols.1
  • PackAge:as you requested
  • ProductionCapacity:10|Kilogram|Day
  • Storage:room temperature
  • Transportation:by courier

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Details:

Product Name: Finasteride
Synonyms: (5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta;l-652,931;mk-0906;n-tert-butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide;1,(5-ALPHA)-ANDROSTAN-4-AZA-3-ONE-17-BETA-(N-TERT-BUTYL-CARBOXAMIDE)
CAS: 98319-26-7
MF: C23H36N2O2
MW: 372.54
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;API;Biochemistry;Steroids;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Vitamin Ingredients;Intracellular receptor;Steroid and Hormone;PROSCAR;Hormone Drugs
Mol File: 98319-26-7.mol
Finasteride Structure
 
Finasteride Chemical Properties
Melting point  253 °C
alpha  405 -59° (c = 1 in methanol)
storage temp.  Store at RT
solubility  DMSO: 32 mg/mL, soluble
form  solid
color  white to beige
Water Solubility  insoluble
Merck  14,4082
CAS DataBase Reference 98319-26-7(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,T,Xi
Risk Statements  22-61-60-36/37/38
Safety Statements  36/37/39-45-53-36-26-24/25
WGK Germany  3
RTECS  CL5245000
Hazardous Substances Data 98319-26-7(Hazardous Substances Data)
MSDS Information
Provider Language
SigmaAldrich English
 
Finasteride Usage And Synthesis
Indications and Usage Finasteride is a basic drug to treat benign prostatic hyperplasia and prostatitis, a synthetic 4-nitrogen steroid hormone compound and a sex hormone drug.
It is used for benign prostatic hyperplasia, men's prostatic fat and other diseases. Finasteride is the only oral drug approved by the US Food and Drug Administration (FDA) to treat male pattern baldness.
Mechanisms of Action Finasteride can selectively inhibit 5α-reductase, changing the conversion process of testosterone into 5α dihydrotestosterone (DHT), decreasing androgen levels in prostate cells, and prostate-specific antigens in serum, decreasing prostate swelling, and increasing urine flow rate, thereby alleviating the symptoms of prostatic hyperplasia. It acts by selectively blocking androgen stimulation of the prostate, but affects sexual function very rarely. Meanwhile, due to blocking of testosterone conversion and reduced synthesis of dihydrotestosterone, it can reduce dihydrotestosterone levels in the serum and scalp hair follicles, recovering the function of previously inhibited hair follicles, promoting hair growth and preventing loss.
Chemical Properties Off-White Crystalline Powder
Uses Inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Antialopecia agent.
Uses anti-androgen, alpha-reductase inhibitor
Uses Treatment of benign prostatic hyperplasia and androgenetic alopecia
Uses Inhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Antialopecia agent
Definition ChEBI: An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.
Biological Activity Antiandrogen that inhibits type II 5 α reductase (IC 50 = 65 nM). Suppresses the conversion of testosterone to dihydrotestosterone. Reduces prostatic dihydrotestosterone levels and prostate size in vivo . Orally active.

 

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