Hydrocortisone high purity Hydrocortisone factory supply Hydrocortisone
Product Name: | Hydrocortisone |
Synonyms: | 11,17a,21-Trihydroxy-4-pragnene-3,20-dione;11-beta,17,21-trihydroxypregn-4-ene-3,20-dione;11beta,17,21-Trihydroxypregn-4-ene-3,20-dione;11-beta,17-alpha,21-trihydroxy-4-pregnene-3,20-dione;11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione;11-beta,17-alpha-trihydroxypregnane-4-ene-3,20-dione;11-beta-hydrocortisone;11beta-Hydrocortisone |
CAS: | 50-23-7 |
MF: | C21H30O5 |
MW: | 362.46 |
EINECS: | 200-020-1 |
Product Categories: | TPI;Steroids;Veterinaries;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;HYDROCORTONE;Isolabel;Hormone Drugs;adrenocortical hormones ' drug;API;Inhibitors;Pharmaceutical intermediates |
Mol File: | 50-23-7.mol |
Hydrocortisone Chemical Properties |
Melting point | 211-214 °C(lit.) |
alpha | 166 º (c=1, C2H5OH 25 ºC) |
Fp | 220°C |
storage temp. | −20°C |
solubility | H2O: 100 mg/mL |
form | powder |
color | White |
Decomposition | 220 ºC |
Merck | 14,4787 |
BRN | 1354819 |
Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 50-23-7(CAS DataBase Reference) |
NIST Chemistry Reference | Hydrocortisone(50-23-7) |
EPA Substance Registry System | Pregn-4-ene-3,20- dione, 11,17,21-trihydroxy-, (11.beta.)-(50-23-7) |
Safety Information |
Hazard Codes | Xn,T,F |
Risk Statements | 63-62-40-39/23/24/25-23/24/25-11 |
Safety Statements | 36/37-45-36-22-16-7 |
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
WGK Germany | 3 |
RTECS | GM8925000 |
TSCA | Yes |
Hazardous Substances Data | 50-23-7(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
ACROS | English |
SigmaAldrich | English |
ALFA | English |
Hydrocortisone Usage And Synthesis |
Chemical Properties | crystalline white powder |
Uses | Principle glucocorticoid hormone produced by adrenal cortex. An anti-inflammatory hormone. |
Uses | glucocorticoid, antiinflammatory |
Uses | Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. |
Definition | ChEBI: A C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immun responses |
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