Bulk offering first...

Bulk offering first-class Ibrutinib 936563-96-1 supplier

Bulk offering first-class Ibrutinib 936563-96-1 supplier

Min.Order / FOB Price:Get Latest Price

100 Gram

Negotiable

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : T/T,,MoneyGram

Keywords

bulk offering Ibrutinib first-class Ibrutinib 936563-96-1 supplier

Quick Details

  • Appearance:White crystal powder
  • Application:Treat B Cell Cancers
  • PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
  • ProductionCapacity:20000|Kilogram|Day
  • Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
  • Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

Superiority:

Bulk offering first-class Ibrutinib 936563-96-1 supplier

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

 

Details:




	

		

			 

		

			Bulk offering first-class Ibrutinib 936563-96-1 supplier

		

			Raw Pharmaceutical 99.9% Purity Ibrutinib For Treat B Cell Cancers CAS 936563-96-1

		

			 

		

			Ibrutinib (Imbruvica) is a small molecule drug that binds permanently to a protein, Bruton's tyrosine kinase (BTK), that is important in B cells; the drug is used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia, a form of non-Hodgkin's lymphoma.

		

			 

		

			Quick View:

		

			 

		

			
				

					
						Product Name
					
						Ibrutinib
				

				

					
						CAS
					
						936563-96-1
				

				

					
						Appearance
					
						White Crystalline Powder
				

				

					
						MF
					
						C25H24N6O2
				

				

					
						MW
					
						440.5
				

				

					
						Purity
					
						99%min
				

				

					
						Application
					
						1.Mantle cell lymphoma (MCL) who have received at least one prior therapy.

						2.Chronic lymphocytic leukemia (CLL) who have received at least one prior therapy.

						3.Waldenstrom's macroglobulinemia.		
				

			
		

		

			 

		

			Descriptions:

		

			 

		

			Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.PCI-32765 (Ibrutinib) is a selective and irreversible pyrrolopyrimidine-based inhibitor of BTK with IC50 of 0.5 nM. [1] PCI-32765 binds irreversibly to Cys-481 in BTK and thus is only active with other kinases with such a modifiable cysteine residue. In DOHH2 cells, in which the BCR pathway can be activated by anti-IgG, PCI-32765 inhibits autophosphorylation of BTK (IC50, 11 nM), BTK's physiological substrate, PLCg (IC50, 29 nm), and downstream ERK (IC50, 13 nm).

		

			 

		

			Ibrutinib is used to treat chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease.

		

			 

		

			COA:

		

			 

		

			
				

					
						Items
					
						Specifications
					
						Results
				

				

					
						Appearance
					
						White to whitish crystal powder
					
						Conforms
				

				

					
						Loss on drying
					
						NMT 0.5%
					
						0.33%
				

				

					
						Residue on ignition
					
						NMT 0.1%
					
						Conforms
				

				

					
						Heavy metal
					
						NMT 20ppm
					
						Conforms
				

				

					
						Assay (HPLC)
					
						NLT 99.5%
					
						99.77%
				

				

					
						Related substances
					
						NMT 0.5%
					
						0.23%
				

				

					
						Single impurity
					
						NMT 0.1%
					
						0.07%
				

				

					
						Conclusion
					
						Complies to the Enterprise standard.
				

			
		

	





	 



	 



	Advantages:



	 



	 



	Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.



	

	1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.



	

	2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.



	

	3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

	

	4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.



	 



	Raw Pharmaceutical 99.9% Purity Ibrutinib For Treat B Cell Cancers CAS 936563-96-1



                        

                

                

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