Cholecalciferol (Vitamin D3) CAS No. 67-97-0 Pharmaceutical Ingredient
Basic Information
product Name: Vitamin D3
Synonyms: Cholecalciferol [USAN:BAN:JAN]; Cholecalciferol; 9,10-Secocholestra-5,7,10(19)-trien-3-ol, (3beta,5Z,7E)-; 7-Dehydrocholesterol, irradiated; 7-Dehydrocholestrol, activated; 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol; 9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol; Activated 7-dehydrocholesterol; Arachitol; Colecalciferol; Colecalciferolo; Colecalciferolo [DCIT]; Colecalciferolum; Colecalciferolum [INN-Latin]; Colecalcipherol; D3-Vicotrat; D3-Vigantol; Delsterol; Deparal; Duphafral D3 1000; EPA Pesticide Chemical Code 202901;
Molecular Formula: C27H44O
Molecular Weight: 384.6377
CAS Registry Number: 67-97-0;8024-19-9;8050-67-7
EINECS: 200-673-2
Packing:25kg/drum
Vitamin D2 VS vitamin D3:
Supplemental vitamin D is available in 2 distinct forms: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Pharmacopoeias have officially regarded these 2 forms as equivalent and interchangeable, yet this presumption of equivalence is based on studies of rickets prevention in infants conducted 70 y ago. The emergence of 25-hydroxyvitamin D as a measure of vitamin D status provides an objective, quantitative measure of the biological response to vitamin D administration. As a result, vitamin D3 has proven to be the more potent form of vitamin D in all primate species, including humans. Despite an emerging body of evidence suggesting several plausible explanations for the greater bioefficacy of vitamin D3, the form of vitamin D used in major preparations of prescriptions in North America is vitamin D2. The case that vitamin D2 should no longer be considered equivalent to vitamin D3 is based on differences in their efficacy at raising serum 25-hydroxyvitamin D, diminished binding of vitamin D2 metabolites to vitamin D binding protein in plasma, and a nonphysiologic metabolism and shorter shelf life of vitamin D2. Vitamin D2, or ergocalciferol, should not be regarded as a nutrient suitable for supplementation or fortification.
What is the most important information I should know about Vitamin D2 (ergocalciferol)
Do not use this medication if you have ever had an allergic reaction to vitamin D, or if you have high levels of calcium or vitamin D in your blood, or if you have any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
Before you take this medication, tell your doctor if you are allergic to any drugs or dyes, or if you have heart disease, coronary artery disease, kidney disease, or an electrolyte imbalance.
Do not take other vitamin or mineral supplements unless your doctor has told you to.
Avoid using calcium supplements or antacids without your doctor's advice. Use only the specific type of supplement or antacid your doctor recommends. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.