TIANFU Tamoxifen citrate

Details:

Product Name: Tamoxifen citrate
Synonyms: 1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate;(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethanamine,citrate(1:;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethylaminecitrate(;2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin2-hydrox;ici46,474;kessar;noltam;tamofen
CAS: 54965-24-1
MF: C32H37NO8
MW: 563.64
EINECS: 259-415-2
Product Categories: Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;API's;Intracellular receptor;Steroid and Hormone;API;SOLTAMOX;Inhibitors
Mol File: 54965-24-1.mol
Tamoxifen citrate Structure
Tamoxifen citrate Chemical Properties
Melting point  140-144 °C
storage temp.  2-8°C
solubility  methanol: soluble50mg/mL, clear, colorless
form  Powder
color  White to off-white
Water Solubility  slightly soluble
Sensitive  Light Sensitive & Hygroscopic
Merck  14,9048
CAS DataBase Reference 54965-24-1(CAS DataBase Reference)
EPA Substance Registry System Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1- butenyl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)(54965-24-1)
Safety Information
Hazard Codes  T,Xi
Risk Statements  45-60-61-22-64-36/37/38
Safety Statements  53-36/37/39-45-36-26
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  KH2387000
HazardClass  IRRITANT

Chemical Properties white to off-white powder
Uses estrogen antagonist, antineoplastic
Uses anti-estrogen, protein kinase C inhibitor, beneficial cardiovascular effects, bone cancer treatment, induces DNA adduct formation
Uses An antiestrogen with potent anti-cancer and PKC inhibitory activities
Biological Activity Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30.